If it is possible, aseotropic evaporation of reaction mixture, HCl flyes away with water, benzene or somethung else. If target is soluble in organic phase better than in water, but sensitive to alkaline media, try to wash with citric acid in water, it takes well some admitures like dymethylformamidex which dont' leave irganic layer at all.
If it is possible, aseotropic evaporation of reaction mixture, HCl flyes away with water, benzene or somethung else. If target is soluble in organic phase better than in water, but sensitive to alkaline media, try to wash with citric acid in water, it takes well some admitures like dymethylformamidex which dont' leave irganic layer at all.
I'm answering too late, however, it can help others. for these kinds of reaction conditions, the best way to remove HCl from the reaction mixture can be the Freeze-pump-thaw procedure.
I'm answering too late, however, it can help others. for these kinds of reaction conditions, the best way to remove HCl from the reaction mixture can be the Freeze-pump-thaw procedure.
Efficient procedure for non acidic compounds: work up your solution with dry K2CO3. If your compound is acidic, you can wash your solution with NaCl solution or citric acid solution.
Efficient procedure for non acidic compounds: work up your solution with dry K2CO3. If your compound is acidic, you can wash your solution with NaCl solution or citric acid solution.
If it is possible, aseotropic evaporation of reaction mixture, HCl flyes away with water, benzene or somethung else. If target is soluble in organic phase better than in water, but sensitive to alkaline media, try to wash with citric acid in water, it takes well some admitures like dymethylformamidex which dont' leave irganic layer at all.
If it is possible, aseotropic evaporation of reaction mixture, HCl flyes away with water, benzene or somethung else. If target is soluble in organic phase better than in water, but sensitive to alkaline media, try to wash with citric acid in water, it takes well some admitures like dymethylformamidex which dont' leave irganic layer at all.
If it is possible, aseotropic evaporation of reaction mixture, HCl flyes away with water, benzene or somethung else. If target is soluble in organic phase better than in water, but sensitive to alkaline media, try to wash with citric acid in water, it takes well some admitures like dymethylformamidex which dont' leave irganic layer at all.
If it is possible, aseotropic evaporation of reaction mixture, HCl flyes away with water, benzene or somethung else. If target is soluble in organic phase better than in water, but sensitive to alkaline media, try to wash with citric acid in water, it takes well some admitures like dymethylformamidex which dont' leave irganic layer at all.
https://www.researchgate.net/publication/282914150_How_to_successfully_convert_a_water-soluble_organic_onium_salt_into_its_free_base_or_change_its_anion_by_using_an_anion-exchanger_resin
Research How to successfully convert a water-soluble organic onium sa...
https://www.researchgate.net/publication/282914150_How_to_successfully_convert_a_water-soluble_organic_onium_salt_into_its_free_base_or_change_its_anion_by_using_an_anion-exchanger_resin
Research How to successfully convert a water-soluble organic onium sa...
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If it is possible, aseotropic evaporation of reaction mixture, HCl flyes away with water, benzene or somethung else. If target is soluble in organic phase better than in water, but sensitive to alkaline media, try to wash with citric acid in water, it takes well some admitures like dymethylformamidex which dont' leave irganic layer at all.
If it is possible, aseotropic evaporation of reaction mixture, HCl flyes away with water, benzene or somethung else. If target is soluble in organic phase better than in water, but sensitive to alkaline media, try to wash with citric acid in water, it takes well some admitures like dymethylformamidex which dont' leave irganic layer at all.
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Dissolve your compound in any polar solvent and wash that organic layer with sodium bicarbonate solution .
Dissolve your compound in any polar solvent and wash that organic layer with sodium bicarbonate solution .
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If your product is solube in a solvent non miscible to water you can wash it with a K2CO3 diluted solution
If your product is solube in a solvent non miscible to water you can wash it with a K2CO3 diluted solution
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I'd like to know about solubility of your product and its functional groups until maybe someone figures out how it should be done.
I'd like to know about solubility of your product and its functional groups until maybe someone figures out how it should be done.
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I'm answering too late, however, it can help others.
for these kinds of reaction conditions, the best way to remove HCl from the reaction mixture can be the Freeze-pump-thaw procedure.
I'm answering too late, however, it can help others.
for these kinds of reaction conditions, the best way to remove HCl from the reaction mixture can be the Freeze-pump-thaw procedure.
More
VOTE
Reaction of water and sodium ethoxide
Reaction of water and sodium ethoxide
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Efficient procedure for non acidic compounds: work up your solution with dry K2CO3. If your compound is acidic, you can wash your solution with NaCl solution or citric acid solution.
Efficient procedure for non acidic compounds: work up your solution with dry K2CO3. If your compound is acidic, you can wash your solution with NaCl solution or citric acid solution.
More
VOTE
If it is possible, aseotropic evaporation of reaction mixture, HCl flyes away with water, benzene or somethung else. If target is soluble in organic phase better than in water, but sensitive to alkaline media, try to wash with citric acid in water, it takes well some admitures like dymethylformamidex which dont' leave irganic layer at all.
If it is possible, aseotropic evaporation of reaction mixture, HCl flyes away with water, benzene or somethung else. If target is soluble in organic phase better than in water, but sensitive to alkaline media, try to wash with citric acid in water, it takes well some admitures like dymethylformamidex which dont' leave irganic layer at all.
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VOTE
If it is possible, aseotropic evaporation of reaction mixture, HCl flyes away with water, benzene or somethung else. If target is soluble in organic phase better than in water, but sensitive to alkaline media, try to wash with citric acid in water, it takes well some admitures like dymethylformamidex which dont' leave irganic layer at all.
If it is possible, aseotropic evaporation of reaction mixture, HCl flyes away with water, benzene or somethung else. If target is soluble in organic phase better than in water, but sensitive to alkaline media, try to wash with citric acid in water, it takes well some admitures like dymethylformamidex which dont' leave irganic layer at all.
More
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