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How to use IC50 to determine bioactivity class?
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Olga Saverskey
How to use IC50 to determine bioactivity class?
Even if there are sensible thresholds, you are not using all of the information you have by posing the problem as a classification. There is probably useful information in how far the true IC50 is away from the class boundaries.
Even if there are sensible thresholds, you are not using all of the information you have by posing the problem as a classification. There is probably useful information in how far the true IC50 is away from the class boundaries.More
My end goal is to be able to "recommend" drug candidates that inhibit the target protein. If my model predicts IC50 accurately, then I can just return the candidates with the lowest predicted IC50s as long as they are below some sensible threshold.More
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