Home >
Community >
Origin of diastereoselectivity in Simmons–Smith cyclopropanation of allylic alcohol
Upvote
26
Downvote
+ Stereoselectivity
+ Carbene
+ Biochemistry
+ Alcohols
Posted by
Mel B.
Origin of diastereoselectivity in Simmons–Smith cyclopropanation of allylic alcohol
Yes. Right after Clayden mentions this stereoselectivity, he proceeds to state that this is due to "coordination between the zinc atom and the hydroxyl group in the transition state" (pp. 1067-8, 1st ed):
Yes. Right after Clayden mentions this stereoselectivity, he proceeds to state that this is due to "coordination between the zinc atom and the hydroxyl group in the transition state" (pp. 1067-8, 1st ed):
Yes. Right after Clayden mentions this stereoselectivity, he proceeds to state that this is due to "coordination between the zinc atom and the hydroxyl group in the transition state" (pp. 1067-8, 1st ed):
Yes. Right after Clayden mentions this stereoselectivity, he proceeds to state that this is due to "coordination between the zinc atom and the hydroxyl group in the transition state" (pp. 1067-8, 1st ed):
More
VOTE