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Standard Free energy of hydrolysis of phosphoenolpyruvate (PEP)
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Mostafa Fathy
Standard Free energy of hydrolysis of phosphoenolpyruvate (PEP)
An answer to this is given in the online version of Berg et al.
Why does phosphoenolpyruvate have such a high phosphoryl-transfer potential? The phosphoryl group traps the molecule in its unstable enol form. When the phosphoryl group has been donated to ATP, the enol undergoes a conversion into the more stable ketone—namely, pyruvate.
Thus, the high phosphoryl-transfer potential of phosphoenolpyruvate arises primarily from the large driving force of the subsequent enol-ketone conversion
Note that Berg et al. use the term “high phosphoryl-transfer potential” or “high phosphoryl group-transfer potential”, as explained in sections 14.1.4 and 14.1.5. These sections are worth reading, and this terminology is worth following.
An answer to this is given in the online version of Berg et al.
Why does phosphoenolpyruvate have such a high phosphoryl-transfer potential? The phosphoryl group traps the molecule in its unstable enol form. When the phosphoryl group has been donated to ATP, the enol undergoes a conversion into the more stable ketone—namely, pyruvate.
Thus, the high phosphoryl-transfer potential of phosphoenolpyruvate arises primarily from the large driving force of the subsequent enol-ketone conversion
Note that Berg et al. use the term “high phosphoryl-transfer potential” or “high phosphoryl group-transfer potential”, as explained in sections 14.1.4 and 14.1.5. These sections are worth reading, and this terminology is worth following.
An answer to this is given in the online version of Berg et al.
Note that Berg et al. use the term “high phosphoryl-transfer potential” or “high phosphoryl group-transfer potential”, as explained in sections 14.1.4 and 14.1.5. These sections are worth reading, and this terminology is worth following.
An answer to this is given in the online version of Berg et al.
Note that Berg et al. use the term “high phosphoryl-transfer potential” or “high phosphoryl group-transfer potential”, as explained in sections 14.1.4 and 14.1.5. These sections are worth reading, and this terminology is worth following.
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