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+ Separation technology
+ Organic chemistry
+ Solvent extraction
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Jukka Lukkari

What is the method for separate out the mixture of Ethyl acetate...

David Duryee  Follow

it is highly impossible but by factional distillation with 6-12 feet projected column .
only 25-40 % will be recover pure solvents.
first collect THF at below 70 degree temperature
then collect mixture at 70-75 degree
and collect final fraction Ethyl acetate at above 75 degree


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Amber Henderson  Follow

Dear Bruce,
Would it be possible to describe in detail how you are going to make the extraction in the lab and what is the organic phase that you are going to use?
Thanks,
rafik

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Alin Stefan  Follow

Hi,
Does anyone know is there a possibility for the separation of ethyl acetate and lube oil? Different methods such as distillation, extraction,... are acceptable.

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Axel Carlson  Follow

Ethyl acetate (EA) is less soluble (8.7g/100g) in water than tetrahydrofuran (THF, solubility 100g/100g) see link. Repeated extractions with water should allow for the removal of most of the THF from the ethyl acetate.
https://www.erowid.org/archive/rhodium/pdf/solvent.miscibility.pdf

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Bob Given  Follow

Dear sir,
Tnanx for your quick reply.
Ethyl acetate and THF having  homogeneous  azeotrope and facing problem to separate out.
i have done fractional distillation and collected 4-5 fractions , but in last fraction also 7% THF  carrying   out.
similarly i have done water washing to mixture to separate out the THF but it is also difficult  after 4-5 times water washing to the mixture.
pl let me know any hybrid method to remove the THF

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Bill Welden  Follow

I would extract the ethyl acetate:THF mixture directly 3 or more times with water containing between 1 and 3M NaCl to remove the THF from the ethyl acetate. I would  use at least 25% of the total volume as the volume of aqueous phase. You will have to experiment to see what concentration of salt and what aqueous:organic ratio is best for the extraction.

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Darla  Follow

Below is given an article that describes how to separate ethyl acetate from ethanol (quite trouble-some unless absolutely necessary). Few patents are issued at USPTO on the same subject - US5993610 , US4569726 patents and more.
"Separation of Ethyl Acetate−Ethanol Azeotropic Mixture Using Hydrophilic Ionic Liquids" - for Google-search

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Dominic Tramonte  Follow

ok thanx sir i will it get back you

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Bradley E. Drury  Follow

Dear Venkat,
If you use a long column in the fractional distillation the chances to get a separation will be very high. Additionally, if the last fraction still contains both solvents, you can re-distill this fraction.
 Please note that petroleum refineries use distillation to separate crude oil where the difference in boiling points between the components is smaller than in your case. 
I believe that using a long column will solve the problem.
Good luck,
Rafik

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Bob Smurdly  Follow

For vapor-liquid equilibrium data on the tetrahydrofuran - ethyl acetate system, see: H.S. Wu, S.I. Sandler, "Vapor-liquid equilibria of tetrahydrofuran systems", J. Chem. Eng. Data, 33(2) 1988, pp. 157–162; http://pubs.acs.org/doi/abs/10.1021/je00052a030

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