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Why is there no U3 snRNP in the spliceosome complex of transcription initiation?
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Oche David
Why is there no U3 snRNP in the spliceosome complex of transcription initiation?
U3 RNA with its proteins forming a complex is localized at nucleolar. The box C'/D motif in U3 snRNA is responsible for this localization. Therefore U3 snRNA does not have a chance to go to mRNA transcription active sites. Instead, U3 snRNP play important roles in ribosomal-RNA processing.
Because of necleolar localization, U3 snRNA is called U3 snoRNA alternatively.
U3 RNA with its proteins forming a complex is localized at nucleolar. The box C'/D motif in U3 snRNA is responsible for this localization. Therefore U3 snRNA does not have a chance to go to mRNA transcription active sites. Instead, U3 snRNP play important roles in ribosomal-RNA processing.Because of necleolar localization, U3 snRNA is called U3 snoRNA alternatively.
U3 RNA with its proteins forming a complex is localized at nucleolar. The box C'/D motif in U3 snRNA is responsible for this localization. Therefore U3 snRNA does not have a chance to go to mRNA transcription active sites. Instead, U3 snRNP play important roles in ribosomal-RNA processing. Because of necleolar localization, U3 snRNA is called U3 snoRNA alternatively.
https://en.wikipedia.org/wiki/Small_nucleolar_RNA_U3
U3 RNA with its proteins forming a complex is localized at nucleolar. The box C'/D motif in U3 snRNA is responsible for this localization. Therefore U3 snRNA does not have a chance to go to mRNA transcription active sites. Instead, U3 snRNP play important roles in ribosomal-RNA processing.Because of necleolar localization, U3 snRNA is called U3 snoRNA alternatively.
https://en.wikipedia.org/wiki/Small_nucleolar_RNA_U3
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