Purulent parotitis, also known as spotted parotitis and chronic recurrent parotitis, is the most common inflammation of the salivary glands and can occur on one side or on both sides. The outcomes of adults and children are significantly different. This is an ascending infection originating from the mouth, usually caused by Staphylococcus aureus that can affect the parotid duct opening. Typical infections occur in elderly or chronic patients with dry mouth due to poor food intake or taking anticholinergic drugs, as well as patients after general anesthesia, with fever, chills, and unilateral parotid pain and swelling; the parotid gland is hard and tender, and the skin above it has erythema and edema. Compression of the parotid gland causes pus to flow out of the parotid duct, and piles of Gram-positive cocci can often be seen after smearing.