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Home > Biochemical Engineering > Nucleoside Drugs (Find 340 items)

Nucleoside Drugs

Capecitabine

(154361-50-9)
An antiproliferative 5-fluorouracil releasing compound

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5-Fluorouracil

(51-21-8)
5-Fluoro Uracil is an active metabolite of Doxifluridine(D556750).

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1,2,4-Triazole

(288-88-0)
1,2,4-Triazole is one of a pair of isomeric chemical compounds with molecular formula C2H3N3, called triazoles, which have a five-membered ring of two carbon atoms and three nitrogen atoms. 1,2,4-Triazole is a basic aromatic heterocycle. 1,2,4-Triazole derivatives find use in a wide variety of applications, most notably as antifungals such as fluconazole and itraconazole.1,2,4-Triazoles can be prepared using the Einhorn–Brunner reaction or the Pellizzari reaction.Unsubstituted 1,2,4-triazole can be prepared from thiosemicarbazide by acyation with formic acid and subsequent cyclization of 1-formyl-3-thiosemicarbazide into 1,2,4-triazole-3(5)-thiol; oxydation of thiol by nitric acid yelds 1,2,4-triazole.The ring structure appears in certain N-heterocyclic carbenes.

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Cytidine

(65-46-3)
increases cell membrane phospholipids

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Thymidine

(50-89-5)
Used for e.g. syntheses of zidovudine. Attributes For further information please contact us Contact

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Decitabine

(2353-33-5)
Decitabine is a potent inhibitor of DNA methylation with IC50 of 438 nM and 4.38 nM in HL-60 and KG1a cells, respectively

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2,6-Dichloropurine

(5451-40-1)
2,6-Dichloropurine is used in the synthesis of 2,6-diamino-substituted purine derivatives as potential cardiomyogenesis inducing agents.

Adenosine5'-monophosphate

(61-19-8)
A useful ligand determinant that facilitates the binding of APS reductase inhibitors.
Nucleoside drugs are an important class of drugs used clinically to treat viral infectious diseases, tumors, and AIDS. Nearly 50% of the currently used antiviral drugs are nucleoside drugs, and the antitumor drugs Cytarabine, Doxifluridine, etc. also belong to the nucleoside class. Nucleoside and deoxynucleoside series derivatives have a variety of biologically active substances, which can be used directly or indirectly as drugs, and play an extremely important role in the treatment of a variety of major diseases.
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