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Mangiferin is a xanthonoid, a chemical compound found in mangoes and in Anemarrhena asphodeloides rhizomes. Mangiferin has effect of hepatinica and choleretic, and is used to therapy hepatitis. Mangiferin is an anti-inflammatory, antivirotic, central nervous system inhibit function and immunologic suppression. Mangiferin has curative effect on chronic bronchitis. Mangiferin has cytotoxicity effect on hepatocellularcarcinoma ce1l, and may induce apoptosis. Mangiferin has the effect of antioxidation and delaying caducity.

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Gamma-mangostin has antioxidant, anti-inflammatory, antibacterial, anti-cancer and other pharmacological activities, and is widely used in medicine γ-Mangostin has anti-inflammatory, anti-oxidant, anti-allergic and bactericidal effects .

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Gartanin is a natural xanthone of mangosteen, with antioxidant, anti-inflammatory, antifungal, neuroprotective and antineoplastic properties. Gartanin induces cell cycle arrest and autophagy and suppresses migration in human glioma cells[1][2].


ChEBI: A member of the class of xanthones that is 9H-xanthene substituted by hydroxy group at positions 1 and 7 and an oxo group at position 9. It has been isolated from Cratoxylum cochinchinense.

garcinone C

Garcinone C, a xanthone derivative, is a natural compound extracted from Garcinia oblongifolia Champ that is used as an anti-inflammatory, analgesia, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels of ATR and 4E-BP1, while efficiently inhibiting the expression levels of cyclin B1, cyclin D1, cyclin E2, cdc2, Stat3 and CDK7. Garcinone C significantly inhibits cell viability of the human Na

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1-Isomangostin hydrate

1-Isomangostin hydrate is the main biologically active compound isolated from the husk of Garcinia mangostana L1, a plant of the genus Garciniaceae. So far, more than 60 xanthones have been isolated from mangosteen peel, leaves, roots, heartwood and other parts. Among them, α-mangostin and 1-isomangostin hydrate account for a larger proportion in mangosteen . They have different levels of bactericidal, anti-inflammatory, anti-dysentery, and ulcer treatment activities.


ChEBI: A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at bpositions 1 and 5 and a methoxy group at position 3.
Xanthones are widely found in plants in nature and are secondary metabolites of plants. Flavonoids are widely distributed in the plant kingdom. Xanthones are usually combined with sugar in plants to form glycosides, and a small part exists in the free state (aglycon). Most plants contain Xanthones, which play an important role in plant growth, development, flowering, fruiting, antibacterial and disease prevention.
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