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    Home > Natural Products > Alkaloids (Find 494 items)



    Dauricine, a bisbenzylisoquinoline alkaloid in Asiatic Moonseed Rhizome, possesses anti-inflammatory activity. Dauricine inhibits cell proliferation and invasion, and induces apoptosis by suppressing NF-κB activation in a dose- and time-dependent manner in colon cancer[1].

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    Sanguinarine, a benzophenanthridine alkaloid derived from the root of Sanguinaria Canadensis, can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB.

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    For the preparation of dopamine D2 receptor antagonists, antimalarial drugs, 5-indolyl-Mannich bases, proliferation inhibitors, human mast cell chymase inhibitors, DL-tryptophan, potentially cruciferous Plant antitoxin brassinolide detoxification inhibitor, 3-vinylindole, serotonin 5-HT6 receptor ligand template, selective protein kinase Cδ (PKCδ) negative regulator

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    Alkaloids exist in nature (mainly plants, but some also exist in animals), a type of nitrogen-containing basic organic compounds, which have alkaloid-like properties. According to the basic structure of alkaloids, it can be divided into about 60 categories. Main types: organic amines, pyrrolidines, pyridines, isoquinolines, indoles, scopolamines, imidazoles, quinazolones, purines, steroids, diterpenes, and others.
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