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Antibiotics

Natamycin

(7681-93-8)
Pimaricin is a macrocyclic tetraene originally isolated from Streptomyces natalensis in 1957. Pimaricin exhibits broad spectrum antifungal activity against yeast and filamentous fungi by binding specifically to ergosterol to block fungal growth. Unlike the related polyenes, nystatin and filipin, pimaricin does not change the permeability of the plasma membrane. Pimaricin is used in the food industry for surface treatment of cheeses as a mould inhibitor.

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Azithromycin

(83905-01-5)
Semi-synthetic macrolide antibiotic; related to Erythromycin A. Antibacterial Macrolide antibiotics, 15-membered nitrogen-containing heterocyclic ring, antibacterial mechanism is similar to erythromycin, but the antibacterial spectrum is broader. It has stronger antibacterial activity against gram-positive bacteria, and has stronger antibacterial activity against gram-negative bacteria such as Haemophilus influenzae, Salmonella, Escherichia coli, Shigella, etc. It is stable to acid and has good tolerance. It has a good therapeutic effect on respiratory infections, skin and soft tissue infections, and sexually transmitted diseases caused by sensitive strains. Antibiotics, used for various infections caused by sensitive bacteria, such as respiratory system infections, skin and soft tissue infections Uses for respiratory tract infections, urinary tract infections, skin and soft tissue infections and sexually transmitted diseases

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Tetracycline Hydrochloride

(64-75-5)
It is a broad-spectrum antibiotic; this product is a broad-spectrum bacteriostatic agent, which has a bactericidal effect at high concentrations.

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Neomycin Sulfate

(1405-10-3)
NEOMYCIN SULFATE is an aminoglycoside antibiotic produced by S. fradiae that inhibits protein translation by binding to the small subunit of prokaryotic ribosomes. It blocks voltage-sensitive Ca2+ channels and is a potent inhibitor of skeletal muscle sarcoplasmic reticulum Ca2+ release. NEOMYCIN SULFATE has been shown to inhibit inositol phospholipid turnover, phospholipase C, and phosphatidylcholine-phospholipase D activity (IC50 = 65 μM). It is highly effective against Gram-positive and Gram-negative bacteria and is commonly used for the prevention of bacterial contamination of cell cultures.

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Lincomycin Hydrochloride

(7179-49-9)
1. An antibiotic produced by Streptomyces lincolnensis. Lincomycin is a lincosamide antibiotic that forms cross-links within the peptidyl transferase loop region of the 23S rRNA. Inhibits bacterial protein synthesis. Antibacterial.
2. Antibacterial;Ribosomal protein synthesis inhibitor
3. Lincomycin hydrochloride is a salt of lincomycin formed at the basic N-methylproline. The hydrochloride salt is the preferred formulation for pharmaceutical use. Lincomycin hydrochloride is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Lincomycin acts by binding to the 23S ribosomal subunit, blocking protein synthesis. Lincomycin has been extensively studied with over 7,000 literature citations.

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Tilmicosin Phosphate

(137330-13-3)
Tilmicosin phosphate is a antibiotic, is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia (Pasteurella) haemolytica.

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Erythromycin

(114-07-8)
Erythromycin can affect bacterial protein synthesis and is generally effective against gram-positive bacteria. It is mainly used to treat infections caused by penicillin G-resistant Staphylococcus aureus. Erythromycin is a commonly used macrolide antibiotic. Its antibacterial spectrum is similar to penicillin. It is mainly used for patients allergic to penicillin or for infections of Staphylococcus aureus resistant to penicillin. It can also be used for streptococcus, pneumococcal infections and diphtheria carrier. This product is an intermediate of macrolide antibiotic derivatives, which belongs to antibacterial antibiotics, and its antibacterial spectrum is similar to penicillin

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Doxycycline Hyclate

(24390-14-5)
1. Tetracycline antibiotics group
2. Antibacterial.

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Oxytetracycline Hydrochloride

(2058-46-0)
Oxytetracycline hydrochloride is a salt prepared from oxytetracycline taking advantage of the basic dimethylamino group which protonates readily to form the salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Like all tetracyclines, oxytetracycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis.

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Amoxicillin Trihydrate

(61336-70-7)
Semi-synthetic antibiotic related to Penicillin. Antibacterial. It is a semi-synthetic broad-spectrum penicillin, the antibacterial spectrum, effect and application are the same as ampicillin Purpose Application: The classification of pharmacologically active substances and relevant animal-derived foods maximum residue limit standards of Commission Regulation (EU) No 37/2010 on December 22, 2009. Semi-synthetic broad-spectrum penicillin, antibacterial spectrum, effect and application are the same as ampicillin.

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Antibiotic refers to a class of secondary metabolites produced by microorganisms (including bacteria, fungi, actinomyces) or higher animals and plants that have anti-pathogens or other activities during their life, and can interfere with the development of other living cells chemical material. With the widespread use and even abuse of antibiotics, antibiotic resistance is posing a threat to global health. Therefore, the development of new antibiotics is imperative, and based on different mechanisms of new antiviotics are at different stages of research and development. The rapid development of biotechnology has promoted the development of antibody drugs and antibacterial peptide drugs, and has become a new force in the field of antibiotics. The development is expected to provide a new way for the prevention and control of pathogenic microorganisms while solving antibiotic resistance. The "Echemi Antibiotics" list mainly supplies APIs for such drugs.

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