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Leucine (abbreviated as Leu or L; encoded by the six codons UUA, UUG, CUU, CUC, CUA, and CUG) is an α-amino acid used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+ 3 form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO− form under biological conditions), and an isobutyl side chain, classifying it as a nonpolar (at physiological pH) amino acid. It is essential in humans—meaning the body cannot synthesize it and thus must obtain from the diet.Leucine is a major component of the subunits in ferritin, astacin, and other "buffer" proteins.

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Additive used in the carbodiimide method for improved amidations and peptide couplings.


Used in the composition of drugs containing Ketoprofen, and Sodium hyaluronate as antiinflammatory agents.

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Used in the preparation of lactone fragments of compadine and lovastatin. 1 Preparation of cis-1,3-polyol, 2 dideoxy nucleoside 3 and spiroacetal cyanohydrin chiral.


10,11-dihydro-10-hydroxy Carbamazepinee is the active metabolite of oxcarbazepine . Oxcarbazepine is rapidly and almost completely converted to 10,11-dihydro-10-hydroxycarbamazepine, which then demonstrates anticonvulsant efficacy by modulating several ion channels and receptors. ?10,11-dihydro-10-hydroxy Carbamazepine is reported to inhibit both voltage-gated Na+ and Ca2+ channels, to potentiate voltage-gated K+ channels, to antagonize adenosine A1 receptors, to increase dopaminergic transmission, and to inhibit glutamate release.
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Anticonvulsants Intermediates are some key chemical raw materials or products in the synthesis process of anticonvulsant drugs. You can easily find high-quality new anticonvulsants intermediates, products and their manufacturers or suppliers on Echemi. We will continue to track the research and development of new products on anticonvulsant medicine.
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