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    Home > API > Inhibitor Drugs (Find 8 items)

    Inhibitor Drugs

    Crizotinib

    (877399-52-5)
    PF-2341066 (Crizotinib) is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nM, respectivley

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    Afatinib

    (439081-18-2)
    BIBW 2992 is an anilino-quinazoline that irreversibly inhibits EGFR and HER2 kinase activity.

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    GW-501516

    (317318-70-0)
    An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream.A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARδ agonist. Exhibits selectivity for PPARδ compared to PPARα and PPARγ. Does not exibit any activity against other nuclear or non-nuclear receptors. Reported to increase cholesterol efflux and ABAC1 expression in macrophages, fibroblasts, and intestinal cells.

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    Selumetinib

    (606143-52-6)
    It is a tight-binding, uncompetitive inhibitor of mitogen-activated protein kinase kinases (MEK) 1 and 2 currently in clinical development.

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    Inhibitors drugs are psychotropic drugs, and common ones include alcohol, opium, and barbiturates, which inhibit or reduce the transmission of nerve impulses in the central nervous system, thereby suppressing (slowing) mental and physical activity. "Inhibitor Drugs" on Echemi mainly supplies APIs for inhibitor drugs.
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