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Inhibitor Drugs


An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream.A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARδ agonist. Exhibits selectivity for PPARδ compared to PPARα and PPARγ. Does not exibit any activity against other nuclear or non-nuclear receptors. Reported to increase cholesterol efflux and ABAC1 expression in macrophages, fibroblasts, and intestinal cells.

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BIBW 2992 is an anilino-quinazoline that irreversibly inhibits EGFR and HER2 kinase activity. Afatinib is an aminocrotonylamino-substituted quinazoline derivative used to treat cancers and diseases of the respiratory tract, lung, gastrointestinal tract, bile duct and gallbladder.

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Sitagliptin phosphate monohydrate

Sitagliptin phosphate is very effective in treating type 2 diabetes. As a new type of anti-diabetic drug, sitagliptin phosphate is blood sugar-dependent, has a moderate hypoglycemic effect, increases insulin secretion without hypoglycemia, effectively reduces hunger and other advantages, and has no nausea, vomiting, edema and increase Side effects such as body weight.


PF-2341066 (Crizotinib) is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nM, respectivley Crizotinib is a small molecule tyrosine kinase inhibitor (TKI) that targets anaplastic lymphoma kinase (ALK), ROS1, and another oncogene receptor tyrosine kinase MET.

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Fingolimod hydrochloride

A cell-permeable aminopropanediol immunosuppressive agent that displays lymphocyte sequestration properties. Fingolimod is a sphingosine-l-phosphate (S1PR) receptor modulator, which binds to the s1P receptor on the surface of lymphocytes after phosphorylation in the body, changes the migration of lymphocytes, and promotes cells to enter lymphatic tissues. Prevent it from leaving the lymphatic tissue and enter the graft, thereby preventing these cells from infiltrating the central nervous system (CNS), thereby achieving the effect of immunosuppression.


It is a tight-binding, uncompetitive inhibitor of mitogen-activated protein kinase kinases (MEK) 1 and 2 currently in clinical development.

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Inhibitors drugs are psychotropic drugs, and common ones include alcohol, opium, and barbiturates, which inhibit or reduce the transmission of nerve impulses in the central nervous system, thereby suppressing (slowing) mental and physical activity. "Inhibitor Drugs" on ECHEMI mainly supplies APIs for inhibitor drugs.
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