Myelofibrosis
Myelofibrosis (MF) is a myeloproliferative disease caused by collagen hyperplasia in the hematopoietic tissue of the bone marrow, and its fibrous tissue seriously affects the hematopoietic function. Primary myelofibrosis is also called "myelosclerosis" and "myeloid metaplasia of unknown cause". This disease has varying degrees of myelofibrosis and extramedullary hematopoiesis mainly in the spleen, followed by the liver and lymph nodes. The typical clinical manifestations are myeloid-erythroblastic anemia and a large number of teardrop-shaped red blood cells. Bone marrow puncture often shows dry extraction, the spleen is often significantly enlarged, and there are varying degrees of bone sclerosis.
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Site of disease:
bone -
Infectious :
Not contagious -
Frequent population:
The age of onset is usually between 50 and 70 years old, ... -
Related symptoms:
Weight loss Liver enlargement Bone pain Weakness Osteosclerosis -
Concurrent disease: