Tropical spastic paraparesis
Tropical spastic paraparesis (TSP) is a neurological endemic disease prevalent in many tropical and subtropical countries. It is an inflammation of the spinal cord caused by chronic infection with human T-lymphocytic virus type 1 (HTLV-1). HTLV-1 associated myelopathy (HAM) originally found in southern Japan is also this disease. It has an insidious onset and slowly progresses, with spastic paraplegia as the main clinical manifestation. Anti-HTLV-1 antibodies are positive in the blood and cerebrospinal fluid. Glucocorticoid treatment has a certain effect.
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Site of disease:
spinal cord -
Infectious :
Not contagious -
Frequent population:
All groups -
Related symptoms:
weakness hyperreflexia sphincteric dysfunction cerebellar ataxia lower limb weakness -
Concurrent disease: