Streptococcal necrosis is an acute suppurative disease caused by β-hemolytic streptococcus infection, characterized by flaky skin necrosis, so it is also called acute streptococcal skin necrosis. β-hemolytic streptococci are extremely pathogenic and can produce hemolysin in the culture medium, causing a wide and transparent hemolytic ring to appear around the colony. Invasion of the human body can quickly destroy local tissues and spread to the surrounding areas. Entering the blood can cause hemolytic reactions. The disease is mainly manifested by redness, swelling, and pain in the local skin at the beginning, which is very similar to erysipelas. It is also called necrotizing erysipelas and hospital necrosis. It can occur after trauma to the limbs, or there may be no obvious history of trauma. After the advent of penicillin, this disease has become rare.