Malignant tumors of the vagina are often secondary and can spread directly from cervical cancer, or from endometrial cancer, ovarian cancer and choriocarcinoma. In addition, bladder, urethral or rectal cancer can also often metastasize to the vagina. Primary vaginal malignancies are very rare, accounting for about 1% of female reproductive organ malignancies. They are mainly squamous cell carcinoma and choriocarcinoma. Others such as adenocarcinoma, sarcoma and malignant melanoma are even rarer. Many obstetricians and gynecologists have only seen a few patients in their medical practice. Since secondary vaginal cancer is more common, the possibility of secondary vaginal cancer should be considered and ruled out before diagnosing a primary tumor.