Antipsychotics refer to drugs that can treat various mental illnesses and various mental symptoms, also known as strong tranquilizers or neuroleptics. According to the chemical structure, they are divided into five categories. Among them, phenothiazines can be divided into three categories according to the different side chain structures: ① aliphatic (such as chlorpromazine); ② piperidine (such as thioridazine); ③ piperazine (such as perphenazine, fluphenazine, trifluoperazine). This type of drug has many clinical uses, and chlorpromazine is the most widely used. After oral administration, the intestinal absorption of this group of drugs is very unstable, and it has the effect of inhibiting intestinal peristalsis, and can often be retained in the intestine for a long time. After absorption, it is distributed in tissues throughout the body, with the highest content in brain and lung tissues. It is mainly metabolized by the liver, and most of it is excreted in the form of glucuronic acid salts or sulfur oxides. The drug excretion time is relatively long, with a half-life of 10 to 20 hours, and the effect can last for several days.