Rosuvastatin calcium structure
Rosuvastatin calcium
White to Off-White Crystalline SolidChEBI: An organic calcium salt that is the hemicalcium salt of rosuvastatin.Rosuvastatin, one of the two new statins launched for the treatment of hypercholesterolemia, has high hepato-selectivity and more potent inhibitory effect on HMG-CoA reductase than the previously marketed statins. In rat hepatocytes, it inhibits cholesterol biosynthesis with an IC50 of 1.12 nM, which is ～100-fold higher potency than pravastatin. Rosuvastatin is synthesiz
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