Meisoindigo structure
Meisoindigo
Meisoindigo(Natura-α; N-Methylisoindigotin; Dian III), a derivative of Indigo naturalis, might induce apoptosis and myeloid differentiation of acute myeloid leukemia (AML).IC50 value:Target: apoptosis inducerin vitro: Meisoindigo inhibited the growth of leukemic cells by inducing marked apoptosis and moderate cell-cycle arrest at the G(0)/G(1) phase. It down-regulated anti-apoptotic Bcl-2, and up-regulated pro-apoptotic Bak and Bax and cell-cycle related proteins, p21and p27. Furthermore
Find 1 Related Holders
Beijing Xiehe Pharmaceutical Co., Ltd.
China
China
API Registration Country
API Active
-
Founded in:
1981-04-04 -
Country:
China -
Address:
Building 7, No. 37 Yongwang Road, Daxing Biomedicine Industry Base, Zhongguancun Science Park, Daxing District, Beijing -
Tax NO.:
91110115101618619W -
Registered Funds:
60 million yuan -
Website:
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Email:
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