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Agomelatine structure

Agomelatine

Agomelatine is a competitive antagonist of human and porcine serotonin (5-HT2C) receptors (pKi = 6.2 and 6.4, respectively) as well as human 5-HT2B receptors (pKi = 6.6). IC50 value: 6.2 (pKi, 5-HT2c); 6.6 (pKi, 5-HT2b)Target: 5-HT2C Receptor; 5-HT2B receptorIt is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor. Activation of 5-HT2C receptors by serotonin inhibits dopamine and norepinephrine release. Antagonism of 5-HT2C results in

Find 24 Related Holders

Beijing Lunarsun Pharmaceutical Co., Ltd.

China

API Registration Country

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Founded in:

2006-03-03
Country:

China
Address:

2508, Floor 25, Building 2, Yard 19, Beiyuan East Road, Chaoyang District, Beijing
Tax NO.:

911101057861847799
Registered Funds:

15.13 million yuan
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Biobetta Pharmaceuticals (Shanghai) Co., Ltd.

China

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Founded in:

2016-07-15
Country:

China
Address:

Room C- 22, Floor 4, Building 1, 198 Huashen Road, China (Shanghai) Pilot Free Trade Zone
Tax NO.:

91310115MA1K3EF230
Registered Funds:

$1 million
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Chongqing Pharscin Pharmaceutical Co., Ltd.

China

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Founded in:

1996-11-04
Country:

China
Address:

Chongqing Rongchang District Industrial Park
Tax NO.:

915002262038944463
Registered Funds:

417.596314 million yuan
Website:

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TianJin TaiPu Pharmaceutical Co., Ltd.

China

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Founded in:

2010-12-16
Country:

China
Address:

No. 101, Xinye 8th Street, Tianjin Economic-Technological Development Zone
Tax NO.:

911201165661239319
Registered Funds:

60 million yuan
Email:

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China UNION Chempharma (SUZHOU) Co., Ltd.

China

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Founded in:

1998-11-10
Country:

China
Address:

No. 6, Jinzi Road, Lili Town, Wujiang District, Suzhou City
Tax NO.:

91320509703698222G
Registered Funds:

10 million yuan
Website:

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China CHINO PHARMA Ltd

China

API Registration Country

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Founded in:

2021-08-10
Country:

China
Address:

Room 402, No. 54, Lane 1277, Zhuanxing East Road, Minhang District, Shanghai
Tax NO.:

91310112MA1GF2KC6D
Registered Funds:

1 million yuan
Website:

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Nantong Chanyoo Pharmatech Co., Ltd.

China

API Registration Country

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Founded in:

2011-05-19
Country:

China
Address:

Yangkou Chemical Industrial Park, Rudong Coastal Economic Development Zone
Tax NO.:

9132062357537648XH
Registered Funds:

100 million yuan
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Jiangsu Hansoh Pharmaceutical Group Co., Ltd.

China

API Registration Country

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Founded in:

1995-07-26
Country:

China
Address:

Lianyungang Economic and Technological Development Zone, Jiangsu Province
Tax NO.:

913207006083959289
Registered Funds:

1,000,000,000 Yuan
Website:

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Hangzhou Allsino Chemicals Co., Ltd.

China

API Registration Country

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Founded in:

2007-02-13
Country:

China
Address:

No. 18, Fenghe Road, Xiaya Town, Jiande City, Hangzhou City, Zhejiang Province
Tax NO.:

913301007966847342
Registered Funds:

203 million yuan
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Jiangsu Weiqida Pharmaceutical Co., Ltd.

China

API Registration Country

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Founded in:

2010-02-08
Country:

China
Address:

No. 1 Linjiang Avenue, Linjiang Town, Haimen District, Nantong City
Tax NO.:

91320684551162575G
Registered Funds:

800 million yuan
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