2-Naphthyl N-methyl-N-(3-tolyl)thiocarbamate structure
2-Naphthyl N-methyl-N-(3-tolyl)thiocarbamate
Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent. Target: AntifungalTolnaftate blocked sterol biosynthesis in fungal cells and cell extracts, with accumulation of squalene. This point of action was confirmed by the direct inhibition of microsomal squalene epoxidase from Candida albicans [1]. Tolnaftate inhibited sterol biosynthesis, At 100 microM, tolnaftate caused up to a 30% release of intracellular [14C]aminoisobutyric acid [2].
Find 5 Related Holders
Fermion Oy
Finland
Finland
API Registration Country
API Active
-
Founded in:
2003-10-07 00:00:00 -
Country:
Finland
SOUVIN PHARMACEUTICALS I PVT LTD
United States
United States
API Registration Country
API Inactive
-
Country:
United States -
Email:
PLANTEX LTD CHEMICAL AND PHARMACEUTICAL WORKS
United States
United States
API Registration Country
API Inactive
-
Country:
United States -
Email:
LUSOCHIMICA SPA
Brazil
Brazil
API Registration Country
API Inactive
-
Country:
Brazil -
Address:
VIA CARNIA, 26, EXTERIOR - EX -
Email:
AARTI DRUGS LIMITED
European Union
European Union
API Registration Country
API Inactive
Recommended Suppliers of 2-Naphthyl N-methyl-N-(3-tolyl)thiocarbamate
-
LEADER BIOCHEMICAL GROUP
CN1 YR
Contact Supplier -
Dingwang Technology (Wuhan) Co., Ltd.
CN1 YR
Contact Supplier -
Xian ZB Biotech Co.,Ltd
CN1 YR
Contact Supplier -
Wuhan Pnq Int Trade Co., Ltd
CN1 YR
Contact Supplier -
Guangzhou Yaoguang Technology Co., Ltd.
CN1 YR
Contact Supplier