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Amifostine structure

Amifostine structure

Amifostine

Amifostine is the trihydrate form of a phosphorylated aminosulfhydryl compound. After dephosphorylation of amifostine by alkaline phosphatase to an active free sulfhydryl (thiol) metabolite, the thiol metabolite binds to and detoxifies cytotoxic platinum-containing metabolites of cisplatin and scavenges free radicals induced by cisplatin and ionizing radiation. The elevated activity of this agent in normal tissues results from both the relative abundance of alkaline phosphatase in normal tissues and the greater vascularity of normal tissues compared to tumor tissues.|A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.

Find 8 Related Holders

Tianjin Zhongrui Pharmaceutical Co., Ltd.
China China

API Registration Country

API Active
  • Founded in:

    2004-03-04
  • Country:

    China China
  • Address:

    East side of Beihuan Road, Chengguan Town, Wuqing District
  • Tax NO.:

    91120000758130319M
  • Registered Funds:

    37.817967 yuan
  • Website:

  • Email:

Kaifeng MINGREN Pharmaceuticals Co., Ltd.
China China

API Registration Country

API Active
  • Founded in:

    2002-11-08
  • Country:

    China China
  • Address:

    No. 8, Yuanqu Road, Huanglong Park, Kaifeng Economic Development Zone
  • Tax NO.:

    91410212744078206P
  • Registered Funds:

    50 million yuan
  • Website:

  • Email:

Sichuan Huiyu Pharmaceutical Co., Ltd.
China China

API Registration Country

API Active
  • Founded in:

    2010-10-12
  • Country:

    China China
  • Address:

    Building 3, No. 333, Hanyang Road, Shizhong District, Neijiang City, Sichuan Province
  • Tax NO.:

    91511000563254776P
  • Registered Funds:

    423.6 million yuan
  • Website:

  • Email:

Nanjing Sike Medicine Industry Co., Ltd.
China China

API Registration Country

API Active
  • Founded in:

    2002-02-22
  • Country:

    China China
  • Address:

    No. 28, Gaoxin Road, Nanjing High-tech Development Zone
  • Tax NO.:

    91320100745351171H
  • Registered Funds:

    177.04298503 yuan
  • Email:

Merro Pharmaceutical Co., Ltd.
China China

API Registration Country

API Active
  • Founded in:

    2015-06-11
  • Country:

    China China
  • Address:

    No. 9, Yingsheng Road, Ganjingzi District, Dalian City, Liaoning Province
  • Tax NO.:

    912102007169138094
  • Registered Funds:

    350 million yuan
  • Website:

  • Email:

Shenzhen Jifu Pharmaceutical Co., Ltd.
China China

API Registration Country

API Active
  • Founded in:

    2004-05-18
  • Country:

    China China
  • Address:

    No. 16, Yuanling South Street, Dapeng Subdistrict, Dapeng New District, Shenzhen
  • Tax NO.:

    914403007619837770
  • Registered Funds:

    27.8125 million yuan
  • Email:

Zhangjiagang City Huatian Pharmaceutical Co., Ltd.
China China

API Registration Country

API Inactive
  • Founded in:

    2003-01-13
  • Country:

    China China
  • Address:

    No. 58, Gangfeng Road, Environmental Protection New Materials Industrial Park, Zhangjiagang Free Trade Zone
  • Tax NO.:

    91320592724177581H
  • Registered Funds:

    6 million yuan
  • Email:

Shanxi Zhendong Taisheng Pharmaceutical Co., Ltd.
China China

API Registration Country

API Inactive
  • Founded in:

    1993-07-05
  • Country:

    China China
  • Address:

    The First Pharmaceutical Park, Economic and Technological Development Zone, Datong City, Shanxi Province
  • Tax NO.:

    91140200602165291J
  • Registered Funds:

    395 million yuan
  • Website:

  • Email:

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