Beijing Peking University WBL Biotech Co., Ltd.
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Founded in:
1994-09-01 -
Country:
China -
Address:
Building 3, No. 2, Yongsheng North Road, Haidian District, Beijing -
Tax NO.:
91110108625906531K -
Registered Funds:
80 million yuan -
Website:
-
Email:
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Telmisartan |
Telmisartan is a specific angiotensin II receptor (ATⅠ type) antagonist that binds to the ATⅠ receptor subtype with high affinity, has no agonist effect at any site, selectively binds to the ATⅠ receptor and the binding effect is long-lasting; it has no affinity for other receptors; it does not inhibit human plasma renin, nor does it block ion channels; it does not inhibit angiotensin converting enzyme II; 80 mg of telmisartan can almost completely inhibit the increase in blood pressure caused by angiotensin II, and the inhibitory effect lasts for 24 hours and can still be measured after 48 hours; the antihypertensive effect gradually becomes obvious within 3 hours after the first dose, and the maximum antihypertensive effect can be obtained 4 weeks after the start of treatment and can be maintained in long-term treatment; after sudden interruption of treatment, blood pressure gradually returns to the pre-treatment level without rebound hypertension; the incidence of dry cough is significantly lower than that of the angiotensin converting enzyme inhibitor treatment group.
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Telmisartan is a specific angiotensin II receptor (ATⅠ type) antagonist that binds to the ATⅠ receptor subtype with high affinity, has no agonist effect at any site, selectively binds to the ATⅠ receptor and the binding effect is long-lasting; it has no affinity for other receptors; it does not inhibit human plasma renin, nor does it block ion channels; it does not inhibit angiotensin converting enzyme II; 80 mg of telmisartan can almost completely inhibit the increase in blood pressure caused by angiotensin II, and the inhibitory effect lasts for 24 hours and can still be measured after 48 hours; the antihypertensive effect gradually becomes obvious within 3 hours after the first dose, and the maximum antihypertensive effect can be obtained 4 weeks after the start of treatment and can be maintained in long-term treatment; after sudden interruption of treatment, blood pressure gradually returns to the pre-treatment level without rebound hypertension; the incidence of dry cough is significantly lower than that of the angiotensin converting enzyme inhibitor treatment group. |
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