Shanghai Ethypharm Pharmaceuticals Co., Ltd.

It can directly relax bronchial smooth muscles, especially those in a state of contraction and spasm. It can also inhibit the release of histamine from mast cells and basophils, and has a certain anti-inflammatory effect. It can strengthen the contraction of the diaphragm and reduce fatigue, thereby improving the contraction of the diaphragm in patients with chronic obstructive pulmonary disease (COPD). It also enhances myocardial contraction and has a slight diuretic effect.

It can directly relax bronchial smooth muscles, especially those in a state of contraction and spasm. It can also inhibit the release of histamine from mast cells and basophils, and has a certain anti-inflammatory effect. It can strengthen the contraction of the diaphragm and reduce fatigue, thereby improving the contraction of the diaphragm in patients with chronic obstructive pulmonary disease (COPD). Theophylline also enhances myocardial contraction and has a slight diuretic effect.

It can directly relax bronchial smooth muscles, especially those in a state of contraction and spasm. It can also inhibit the release of histamine from mast cells and basophils, and has a certain anti-inflammatory effect. It can strengthen the contraction of the diaphragm and reduce fatigue, thereby improving the contraction of the diaphragm in patients with chronic obstructive pulmonary disease (COPD). Theophylline also enhances myocardial contraction and has a slight diuretic effect.

This product is a calcium channel blocker, and its action is related to the inhibition of calcium ion influx during myocardial and vascular smooth muscle depolarization. It can effectively dilate the epicardial and subendocardial coronary arteries, relieve spontaneous angina pectoris or angina pectoris caused by coronary artery spasm induced by ergonovine; by slowing down the heart rate and lowering blood pressure, it can reduce myocardial oxygen demand, increase exercise tolerance and relieve exertional angina pectoris. It can relax vascular smooth muscle, reduce peripheral vascular resistance, and lower blood pressure; the extent of its blood pressure reduction is related to the degree of hypertension, and only slightly reduces blood pressure in people with normal blood pressure. It has a negative inotropic effect and can slow down the conduction of the sinoatrial node and atrioventricular node.

By inhibiting the influx of calcium ions into the coronary vessels and the smooth muscle cells of the peripheral/peripheral vessels, it can dilate blood vessels, improve myocardial ischemia and lower blood pressure. 1 Effect on myocardial ischemia: By dilating the main coronary artery and side branches and inhibiting coronary spasm, it increases the blood flow to the ischemic part of the myocardium. It reduces myocardial oxygen consumption while reducing the afterload of the heart, lowering the heart rate and not reducing cardiac output. By inhibiting the influx of excessive calcium ions into ischemic myocardial cells, it protects myocardial cells, improves energy metabolism and reduces the area of ischemic areas. 2 Effect on blood pressure: It has no significant effect on normal blood pressure. It does not reduce blood flow to the brain and kidneys while lowering blood pressure for hypertension. It can also inhibit myocardial hypertrophy and thickening of vascular walls caused by hypertension. 3 Effect on the cardiac conduction system: It slightly prolongs the conduction between the sinoatrial node and the His bundle (A-H) and has no significant effect on the conduction between the His bundle and the Purkinje fibers (A-V).