This product is a calcium channel blocker, and its action is related to the inhibition of calcium ion influx during myocardial and vascular smooth muscle depolarization. This product can effectively dilate the epicardial and subendocardial coronary arteries, relieve spontaneous angina pectoris or angina pectoris caused by coronary artery spasm induced by ergonovine; by slowing down the heart rate and lowering blood pressure, it reduces myocardial oxygen demand, increases exercise tolerance and relieves exertional angina pectoris. This product can relax vascular smooth muscle, reduce peripheral vascular resistance, and lower blood pressure; the extent of its blood pressure reduction is related to the degree of hypertension, and only slightly reduces blood pressure in people with normal blood pressure. This product has a negative inotropic effect and can slow down the conduction of the sinoatrial node and atrioventricular node.

This product is a calcium channel blocker, and its action is related to the inhibition of calcium ion influx during myocardial and vascular smooth muscle depolarization. This product can effectively dilate the epicardial and subendocardial coronary arteries, relieve spontaneous angina pectoris or angina pectoris caused by coronary artery spasm induced by ergonovine; by slowing down the heart rate and lowering blood pressure, it reduces myocardial oxygen demand, increases exercise tolerance and relieves exertional angina pectoris. This product can relax vascular smooth muscle, reduce peripheral vascular resistance, and lower blood pressure; the extent of its blood pressure reduction is related to the degree of hypertension, and only slightly reduces blood pressure in people with normal blood pressure. This product has a negative inotropic effect and can slow down the conduction of the sinoatrial node and atrioventricular node.

This product is a calcium channel blocker. It inhibits the transmembrane influx of calcium ions from the extracellular to the intracellular by acting on the calcium ion channels in the myocardium, coronary vessels, peripheral blood vessels, and atrioventricular node, reducing the concentration of intracellular calcium ions, but does not change the serum calcium concentration. It relieves and prevents the contraction of myocardial and vascular smooth muscle cells, has the effects of dilating coronary arteries and peripheral blood vessels, improving myocardial hypertrophy and prolonging the conduction time of the atrial blockage node, and can effectively treat hypertension, angina pectoris, and arrhythmia. 1. Improvement of angina pectoris: ① This product can effectively dilate the coronary arteries and collateral vessels under the epicardium and endocardium, increase the blood flow of the coronary arteries and collateral vessels, thereby increasing the ischemic myocardium and blood flow, improving myocardial ischemia, and relieving angina pectoris. ② Inhibit the spasm of coronary vessels, and has obvious clinical efficacy on the backlog of angina pectoris caused by coronary artery spasm. ③ Dilate peripheral blood vessels, reduce the afterload of the heart, slow down the heart rate, and reduce the work of the heart, which has a significant improvement effect on angina pectoris caused by increased cardiac oxygen consumption. 2. Improvement of hypertension: ① This product relaxes the smooth muscle of peripheral blood vessels and reduces the resistance of peripheral blood vessels, thereby lowering blood pressure. The extent of blood pressure reduction is related to the degree of hypertension. People with normal blood pressure only show a slight impact. ② This product does not affect the blood supply of important organs such as the heart, brain, and kidneys while lowering blood pressure. ③ This product reduces the afterload of the heart, inhibits myocardial contraction, and has an improvement effect on myocardial hypertrophy caused by hypertension. 3. Effect on the conduction system: This product has an inhibitory effect on the conduction of the atrial node and the atrioventricular node. The clinical manifestations are no increase in heart rate or slowing down of heart rate, prolonged atrioventricular conduction time, etc. Carcinogenic, mutagenic and reproductive toxic effects. There are reports that rats took this product for 24 months and mice took this product for 32 months without carcinogenicity. In vitro bacterial experiments did not find mutagenic effects. Animal experiments have confirmed that this product has no significant effect on fertility.

This product is an angiotensin converting enzyme (ACE) inhibitor. After oral administration, it is converted into the active metabolite imidaprilat in the body, which can inhibit the activity of ACE, prevent angiotensin I from converting into angiotensin II, dilate peripheral blood vessels, reduce vascular resistance, and produce a hypotensive effect.

This product is an angiotensin converting enzyme (ACE) inhibitor. After oral administration, it is converted into the active metabolite imidaprilat in the body, which can inhibit the activity of ACE, prevent angiotensin I from converting into angiotensin II, dilate peripheral blood vessels, reduce vascular resistance, and produce a hypotensive effect.