Quinolone antibacterial drugs, the mechanism of action is to inhibit bacterial DNA helicase, with a broad-spectrum antibacterial effect, and have strong antibacterial activity against Enterobacter bacteria such as Escherichia coli, Klebsiella, Proteus, Shigella, Salmonella typhi, etc., as well as influenza bacillus, Neisseria, etc., and also have certain antibacterial effects on Staphylococcus aureus and Pseudomonas aeruginosa. It has only a mild effect on pneumococci, various groups of streptococci and enterococci.

Quinolone antibacterial drugs inhibit bacterial DNA helicase and have a broad-spectrum antibacterial effect. They have strong antibacterial activity against Enterobacter bacteria such as Escherichia coli, Klebsiella, Proteus, Shigella, Salmonella typhi, etc., as well as influenza bacillus and Neisseria. They also have certain antibacterial effects on Staphylococcus aureus and Pseudomonas aeruginosa. They have only mild effects on pneumococci, various groups of streptococci and enterococci.

Quinolone antibiotics have obvious antibacterial effects on Gram-positive bacteria and Gram-negative bacteria; they also have good antibacterial effects on mycoplasma, chlamydia, Legionella, anaerobic bacteria and mycobacteria. They have a bactericidal effect by inhibiting the action of bacterial DNA gyrase.

Azithromycin is a 15-membered macrolide antibiotic that inhibits RNA-dependent protein synthesis by binding to the 50S subunit of bacterial ribosomes. Its antibacterial spectrum includes a variety of Gram-positive aerobic bacteria (such as Staphylococcus aureus, Streptococcus pyogenes, etc.), Gram-negative aerobic bacteria (such as Haemophilus influenzae, Moraxella catarrhalis, etc.), anaerobic bacteria (such as Bacteroides fragilis, Propionibacterium acnes, etc.), sexually transmitted disease microorganisms (such as Treponema pallidum, Neisseria gonorrhoeae), and other microorganisms (such as Mycoplasma pneumoniae, Chlamydia trachomatis, etc.).

Azithromycin is a 15-membered macrolide antibiotic. In vitro tests have shown that azithromycin has antibacterial effects on a variety of common clinical pathogens, including Gram-positive aerobic bacteria, Gram-negative aerobic bacteria, anaerobic bacteria, sexually transmitted disease microorganisms and other microorganisms. The mechanism of action is the same as that of erythromycin, mainly binding to the 50S subunit of the bacterial ribosome and inhibiting RNA-dependent protein synthesis.