Henan Runhong Pharmaceutical Co., Ltd.

No specific pharmacological effects mentioned

It takes a long time to take effect, but lasts for a long time, up to 6-8 hours, and has antipyretic and analgesic effects.

The antipyretic and analgesic effects take effect quickly and have strong analgesic efficacy, ensuring that the antipyretic and analgesic effects are produced within 15-20 minutes.

It has a direct relaxant effect on the smooth muscles of the respiratory tract; it partly increases the intracellular cAMP content by inhibiting phosphodiesterase; it partly produces a bronchodilator effect by releasing endogenous adrenaline and norepinephrine; as a purine receptor blocker, it can counteract the contractile effect of adenine and other substances on the respiratory tract; it enhances the contractility of the diaphragm and improves respiratory function; it has a weak effect of relaxing the smooth muscles of the coronary arteries, peripheral blood vessels and bile ducts; it slightly increases the contractility of the heart and has a diuretic effect.

It has neuroprotective effects, promotes brain metabolism, improves brain microcirculation, and selectively increases brain blood flow. Specifically, it relieves the cytotoxic effects induced by excitatory amino acids, inhibits sodium and calcium channels, NMDA and AMPA receptors, and enhances the neuroprotective effects of adenosine; increases the intake and consumption of glucose and oxygen by brain tissue, improves brain hypoxia tolerance, increases ATP concentration and ATP/AMP ratio, promotes the renewal of norepinephrine and 5-hydroxytryptamine, and has an antioxidant effect; inhibits platelet aggregation, reduces pathological blood viscosity, increases red blood cell deformability, and promotes oxygen transport in tissues; increases the percentage of cardiac output supplied to the brain, reduces cerebrovascular resistance without affecting systemic circulation parameters, and promotes blood supply to low-perfusion ischemic areas.

1. Neuroprotective effect: relieves the cytotoxic effect induced by excitatory amino acids, inhibits voltage-dependent sodium and calcium channels, NMDA and AMPA receptors, and enhances the neuroprotective effect of adenosine; 2. Promotes brain metabolism: increases the intake and consumption of glucose and oxygen by brain tissue, improves the brain's tolerance to hypoxia, enhances the transport of glucose across the blood-brain barrier, selectively inhibits calcium calmodulin-dependent cGMP-phosphodiesterase, increases cGMP and cAMP levels in the brain, increases ATP concentration and ATP/AMP ratio, promotes the renewal of norepinephrine and 5-hydroxytryptamine, and has an antioxidant effect; 3. Improves brain microcirculation: inhibits platelet aggregation, reduces pathological blood viscosity, increases red blood cell deformability, inhibits red blood cell uptake of adenosine, and promotes tissue oxygen transport by reducing red blood cell oxygen affinity; 4. Selectively increases cerebral blood flow: increases the percentage of cardiac output supplied to the brain, reduces cerebrovascular resistance without affecting systemic circulation parameters, and promotes blood supply to damaged hypoperfused ischemic areas.