Three Pharmaceutical Drug Group (Wuhu) Co., Ltd.

This product has a broad-spectrum antibacterial effect, especially high antibacterial activity against aerobic Gram-negative bacilli. It has good antibacterial activity in vitro against the following bacteria: most bacteria of the Enterobacteriaceae family, including Citrobacter, Enterobacter cloacae, Enterobacter aerogenes, Escherichia coli, Klebsiella, Proteus, Salmonella, Shigella, Vibrio, Yersinia, etc. It often also has antibacterial activity against multi-drug resistant bacteria. It has high antibacterial activity against penicillin-resistant Neisseria gonorrhoeae, enzyme-producing influenza bacilli and Moraxella. It has antibacterial activity against most strains of Pseudomonas such as Pseudomonas aeruginosa. This product has antibacterial activity against methicillin-sensitive Staphylococcus aureus, and only moderate antibacterial activity against Streptococcus pneumoniae, hemolytic Streptococcus and Enterococcus faecalis. It has good antimicrobial activity against Chlamydia trachomatis, Mycoplasma, Legionella, and also has antibacterial activity against Mycobacterium tuberculosis and atypical mycobacteria. It has poor antibacterial activity against anaerobic bacteria. Ofloxacin is a bactericide that acts on the A subunit of bacterial DNA gyrase, inhibiting DNA synthesis and replication, leading to bacterial death.

Adrenal cortical hormones have anti-inflammatory and anti-allergic effects, can inhibit the proliferation of connective tissue, reduce the permeability of capillaries and cell membranes, reduce inflammatory exudates, and inhibit the formation and release of histamine and other inflammatory mediators.

Has antibacterial and analgesic effects and has a cooling sensation

Adrenal cortex hormone drugs. This product has anti-inflammatory and anti-allergic effects, can inhibit the proliferation of connective tissue, reduce the permeability of capillary walls and cell membranes, reduce inflammatory exudate, and inhibit the formation and release of histamine and other toxic substances.

1. Anti-inflammatory effect 2. Selective pharmacological effect on various cells 3. Anti-proliferative effect 4. Immunosuppressive effect

1. Anti-inflammatory effect: Highly effective fluorinated and chlorinated corticosteroids, with anti-inflammatory, anti-itching and vasoconstrictive effects; by increasing the responsiveness of α receptors to catecholamine, activating adenylate cyclase to increase cAMP production, inhibiting phosphoethylesterase to reduce cAMP destruction, and inhibiting the release of histamine. 2. Selective pharmacological effects on various types of cells: reducing the number of T lymphocytes, monocytes, and eosinophils, inhibiting lymphocyte proliferation and cytokine production, inhibiting macrophage differentiation and phagocytic activity, inhibiting neutrophil adhesion, reducing vascular endothelial cell permeability, inhibiting fibroblast proliferation and collagen synthesis, and inhibiting sebaceous gland cell activity. 3. Anti-proliferative effect: It has anti-mitotic effect, reduces PNA transcription, thereby reducing DNA synthesis, affecting DNA repair, and thinning the epidermis, especially the greatest effect on collagen synthesis. 4. Immunosuppressive effect: By binding to the corticosteroid receptors in the cytoplasm, a series of reactions occur, activating the expression of lytic genes, inducing nuclear DNA cleavage in lymphocytes and directly killing lymphocytes.