Recombinant human interleukin-2 for injection
Function and Efficacy
This product is a lymphokine that can proliferate cytotoxic T cells, natural killer cells and lymphokine-activated killer cells and enhance their killing activity. It can also promote lymphocytes to secrete antibodies and interferons, and has anti-viral, anti-tumor and immune enhancement effects. Long-term toxicity tests on animals have shown that no abnormalities are found in blood picture, blood and urine biochemical tests, circulatory system examinations, and pathological histological examinations.
Ingredients
Recombinant human interleukin-2, human serum albumin
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Human serum albuminExcipients |
This product is a lymphokine that can proliferate cytotoxic T cells, natural killer cells and lymphokine-activated killer cells and enhance their killing activity. It can also promote lymphocytes to secrete antibodies and interferons, and has anti-viral, anti-tumor and immune enhancement effects. Long-term toxicity tests on animals have shown that no abnormalities are found in blood picture, blood and urine biochemical tests, circulatory system examinations, and pathological histological examinations. More |
70024-90-7 | 2 |
Appearance
This product is a white, thin, loose shell, easily soluble in water, and after dissolution it is a transparent liquid with no visible insoluble matter.
Indication
It is used to treat adult metastatic renal cell carcinoma (RCC) and melanoma and other malignant tumors, and is also suitable for the control of cancerous pleural effusion and ascites.
Usage and Dosage
This product should be used under the guidance of a clinical physician. Dissolve it with sterile water for injection before injection. The specific usage, dosage and course of treatment vary according to the disease. The following methods are generally used: 1. Systemic administration: subcutaneous or intramuscular injection: recombinant human interleukin-2.5 to 1 million IU/m2, subcutaneous or intramuscular injection 2 to 3 times/week, 4 to 6 weeks as a course of treatment. 2. Regional and local administration (1) Thoracic and abdominal cavity injection: used for cancerous pleural and abdominal effusion, recombinant human interleukin-2.3 to 1 million IU/m2/time, try to remove the effusion in the cavity and then inject, 1 to 2 times/week, 2 to 4 weeks (or the effusion disappears) as a course of treatment. (2) Local administration to tumor lesions: limited to research and observation by oncologists
Adverse Reactions
The most common adverse reactions are fever and chills, which are related to the dosage of the drug. Generally, the fever is transient (around 38°C), and there may also be chills and high fever. The body temperature can return to normal 3 to 4 hours after stopping the drug. Some patients may experience nausea, vomiting, and cold-like symptoms. Subcutaneous injections may cause local redness, swelling, nodules, and pain. All side effects can recover on their own after stopping the drug. When used in larger doses, this product may cause capillary leak syndrome, manifested as hypotension, peripheral edema, temporary renal insufficiency, etc. The safe dosage should be strictly controlled when using this product, and symptomatic treatment can be given if the above reactions occur.
Precautions
1. Patients with a history of allergy to the ingredients of this product. 2. Patients with high fever, severe heart disease, hypotension, severe heart and kidney insufficiency, abnormal lung function or those who have undergone organ transplantation.
Special Population Medication
Precautions for children: Precautions for pregnancy and lactation: Pregnant women should use with caution. Precautions for the elderly:
Drug Interactions
Not yet clear
Storage
2~8℃, keep away from light, valid for 3 years
Packaging Specification
1 million IU
Validity Period
24 months
Manufacturer
Shenyang Sunshine Pharmaceutical Co., Ltd.
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Founded in:
1993-01-03 -
Address:
No. 3, 1A, No. 10 Road, Shenyang Economic and Technological Development Zone -
Tax NO.:
9121010660460338X6 -
Registered Funds:
1,000,000,000 Yuan -
Website:
-
Email: