Azithromycin for injection

1 Azithromycin belongs to the macrolide antibiotic class. 2 The mechanism of action of this product is the same as that of erythromycin. It mainly binds to the 50S subunit of bacterial ribosomes and inhibits RNA-dependent protein synthesis.

The main ingredient of this product is azithromycin. Its chemical name is (2R, 3S, 4R, 5R, 8R, 10R, 11R, 12S, 13S, 14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one. Structural formula: (see azithromycin dry suspension) Molecular formula: C38H72N2O12 Molecular weight: 749

This product is white or off-white loose lumps.

This product is suitable for the following infections caused by sensitive pathogenic strains. 1 Community-acquired pneumonia caused by Chlamydia pneumoniae, Haemophilus influenzae, Legionella pneumophila, Moraxella catarrhalis, Mycoplasma pneumoniae, Staphylococcus aureus or Streptococcus pneumoniae that requires intravenous drip treatment first. 2 Pelvic inflammatory disease caused by Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycoplasma hominis that requires intravenous drip treatment first.

Dissolve this product in an appropriate amount of water for injection to prepare 0.1g/ml, then add it to 250ml or 500ml of sodium chloride injection or 5% glucose injection. The final azithromycin concentration is 1.0-2.0mg/ml, and then drip it intravenously. The concentration is 1.0mg/ml, and the drip time is 3 hours; the concentration is 2.0mg/ml, and the drip time is 1 hour. 1 Treatment of community-acquired pneumonia: 0.5g for adults once a day, once a day, for at least 2 consecutive days, followed by switching to azithromycin oral preparations 0.5g a day, 7 to 10 days as a course of treatment. The time to switch to oral treatment should be determined by the physician based on the clinical treatment response. 2 Treatment of pelvic inflammatory disease: 0.5g for adults once a day, once a day, after 1 or 2 days of medication, switch to azithromycin oral preparations 0.25g a day, 7 days as a course of treatment. The time to switch to oral treatment should be determined by the physician based on the clinical treatment response.

1 If you feel unwell while taking this product, tell your doctor or pharmacist as soon as possible. If the situation is urgent, stop taking the medicine first. 2 If the medication is used reasonably, the drug can bring you satisfactory therapeutic effects. It may also cause some adverse reactions, but not everyone will experience them. You may not encounter any of them, so don't be nervous. The following are possible adverse reactions of azithromycin: 3 Gastrointestinal reactions such as abdominal pain, diarrhea (loose stools), upper abdominal discomfort (pain or cramps), nausea, and vomiting may occur after taking the medicine. The incidence is significantly lower than that of erythromycin. 4 A small number of patients may experience transient neutropenia and elevated serum aminotransferase. 5 Occasionally, allergic reactions such as mild to moderate abdominal distension, dizziness, headache, fever, rash, and joint pain may occur. 6 Anaphylactic shock, angioedema, and cholestatic jaundice are extremely rare.

It is contraindicated in patients who are allergic to azithromycin, erythromycin, or any other macrolide drugs.

Precautions for children: The safety of this product for patients under 16 years old is not clear. Precautions for pregnancy and lactation: Animal experiments show that this product has no effect on the fetus, but there is still a lack of experience in its use in pregnant women, so the pros and cons must be fully weighed before using it in pregnant women. There is no data to show whether this product can be secreted into breast milk, so the use of this product in lactating women must be considered with caution. Precautions for the elderly:

1. If you take any other medicines, please tell your doctor or pharmacist, including any over-the-counter medicines purchased from pharmacies, supermarkets or health food stores. These medicines may be affected by this product, or this product may affect the efficacy of other medicines. You may need different dosages or need to take different medicines. Please follow the doctor's advice. 2. Doctors and pharmacists may have more information on precautions for taking this product. 3. Some medicines (or foods) may interfere with this product, including: ① It is not suitable to take it at the same time with antacids containing aluminum or magnesium, which can reduce the peak blood concentration of this product; if it must be used together, this product should be given 1 hour before or 2 hours after taking the above drugs. ② When used in combination with theophylline, the concentration of the latter in plasma can be increased, and the plasma theophylline level should be detected. ③ When used in combination with warfarin, the prothrombin time should be checked. ④ When used with the following drugs at the same time, it is recommended to observe the patient closely: Digoxin: Increases digoxin levels. Ergotamine or dihydroergotamine: acute ergot toxicity, symptoms are severe peripheral vasospasm and dysesthesia (pain on touch). Triazolam: by reducing the degradation of triazolam, the pharmacological effect of triazolam is enhanced. Cytochrome P450 system metabolites: increase the levels of carbamazepine, terfenadine, cyclosporine, cyclohexylbarbital, and phenytoin in serum. ⑤ Combined use with rifabutin will increase the toxicity of the latter.

Sealed and light-proof.

0.25g (250,000 units)

Hangzhou Ausia Biological Technology Co., Ltd.

• Founded in:

  1993-02-23

• Address:

  No. 1, No. 1 Street, Hangzhou Economic and Technological Development Zone, Zhejiang Province

• Tax NO.:

  91330101609134463G

• Registered Funds:

  65 million yuan

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