Recombinant human interleukin-2 (125Ala) for injection

IL-2 can significantly enhance the immune function of T cells, macrophages, and NK cells, and can also induce killer cells, LAK cells, and activate tumor-infiltrating lymphocytes (TIL). In addition, IL-2 and other cytokines have a synergistic effect of enhancing immune function, which promotes the localization of tumors and infection lesions. Therefore, IL-2 has significant immune enhancement and anti-tumor effects. Compared with the prototype IL-2, the modified IL-2 has increased specific activity and thermal stability, and the pharmacological action time in vivo is prolonged.

IL-2 can significantly enhance the immune function of T cells, macrophages, and NK cells, and can also induce killer cells, LAK cells, and activate tumor-infiltrating lymphocytes (TIL). In addition, IL-2 and other cytokines have a synergistic effect of enhancing immune function, which promotes the localization of tumors and infection lesions. Therefore, IL-2 has significant immune enhancement and anti-tumor effects. Compared with the prototype IL-2, the modified IL-2 has increased specific activity and thermal stability, and the pharmacological action time in vivo is prolonged.

1. It is used for the treatment of malignant tumors such as renal cell carcinoma, melanoma, breast cancer, bladder cancer, liver cancer, colorectal cancer, lymphoma, lung cancer, etc., and for the control of cancerous pleural effusion and ascites. It can also be used for the cultivation of lymphokine-activated killer cells.

1. Thoracic and abdominal injection: 125AlaII-21-2 million IU/time, 1-2 times a week, 2-4 weeks as a course of treatment. 2. Local injection: The dose is determined according to the size of the cancer focus, each time each lesion is not less than 6.1 million IU, once every other day, 4 weeks as a course of treatment. 3. Subcutaneous injection: 125AlaII-26-1 million IU/m3, once a day, 5 times a week, 4 weeks as a course of treatment. 4. Intravenous drip: 125AlaII-24-800,000 IU/m3, once a day, slow drip, 5 times a week, 4 weeks as a course of treatment.

Common side effects during treatment include fever, chills, fatigue, nausea, mild loss of appetite, etc. Other rare side effects include local reactions, rashes, decreased blood pressure, water retention, elevated transaminases, etc. Most of the above side effects are mild and easy to tolerate, and can be relieved on their own after stopping the drug. If necessary, indomethacin or blood pressure can be given to treat the symptoms.

This product is contraindicated for patients with a history of allergic reaction to interleukin-2 or other serious diseases who cannot tolerate the side effects of this drug.

This product is contraindicated for patients with a history of allergic reaction to interleukin-2 or other serious diseases who cannot tolerate the side effects of this drug.

Store at 2-8℃.

200,000 IU

Beijing SL Pharmaceutical Co., Ltd.

• Founded in:

  1994-12-24

• Address:

  4th Floor, Building 1, Bitongyuan, No. 69, Fushi Road, Haidian District, Beijing

• Tax NO.:

  91110000102299779W

• Registered Funds:

  1,027.35 million yuan

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