On ECHEMI
Home > Drugs > Cyclosporine Soft Capsules

Cyclosporine Soft Capsules

Function and Efficacy

Not yet clear.

Ingredients

The main ingredient of this product is ciclosporin, and its chemical name is: cyclo(E)-(2S,3R,4R)-3-hydroxy-4-methyl-2-(methylamino-6-octenyl-L-α-aminobutyryl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-valyl. Molecular formula C62H111N11O12 molecular weight 1202.625

Appearance

This product is a soft capsule, the contents of which are yellow or light yellow-brown clear liquid.

Indication

Organ transplantation, bone marrow transplantation, autoimmune diseases such as endogenous uveitis, rheumatoid arthritis, atopic dermatitis, psoriasis, etc.; nephrotic syndrome.

Usage and Dosage

Except for some cases where intravenous infusion of sanoflagellamine concentrate is required, oral neosanoflagellamine treatment is recommended for most cases. Neosanoflagellamine is absorbed faster than standard sanoflagellamine oral solution (mean peak time is 1 hour earlier, mean peak concentration is increased by 59%), and its bioavailability (AUC) is increased by an average of 29% in renal transplant patients receiving maintenance doses. In patients with extremely poor oral absorption of standard sanoflagellamine (especially those taking large oral doses), the increase in cyclosporine bioavailability they obtain after converting to an equal amount of neosanoflagellamine may exceed 100%. The total daily dose of neosanoflagellamine should be taken twice (morning and evening).

Adverse Reactions

Not yet clear.

Precautions

Allergic to cyclosporine and any of its excipients. (See Ingredients and Precautions) The following are additional contraindications for non-transplant indications: Patients with renal insufficiency other than nephrotic syndrome, who present with a moderate increase in pre-drug serum creatinine values related to the condition (up to 200 micromol/L for adults and 140 micromol/L for children), so this product is allowed to be used with caution to alleviate the condition. Uncontrolled hypertension Uncontrolled infection Any malignancy other than skin cancer or precancerous changes (see psoriasis and skin tumors in Dosage/Usage and Adverse Reactions).

Special Population Medication

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.

Drug Interactions

Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.

Storage

Keep away from light, sealed and stored at room temperature

Packaging Specification

25 mg

Validity Period

24 months

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.