Nicorandil Tablets
Function and Efficacy
Anti-angina drug. This product belongs to the nitrate compound, which has the effect of preventing the free calcium ions in cells, increasing the permeability of cell membranes to potassium ions, dilating coronary blood vessels, continuously increasing coronary blood flow, and inhibiting coronary artery spasm. When dilating coronary blood vessels, it does not affect blood pressure, heart rate, myocardial contractility, and myocardial oxygen consumption. This product also has the effect of inhibiting platelet aggregation and preventing thrombosis.
Ingredients
The main ingredient of this product is Nicorandil, and its chemical name is: nicotinamide ethyl nitrate.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| NicorandilIngredients |
Anti-angina drug. This product belongs to the nitrate compound, which has the effect of preventing the free calcium ions in cells, increasing the permeability of cell membranes to potassium ions, dilating coronary blood vessels, continuously increasing coronary blood flow, and inhibiting coronary artery spasm. When dilating coronary blood vessels, it does not affect blood pressure, heart rate, myocardial contractility, and myocardial oxygen consumption. This product also has the effect of inhibiting platelet aggregation and preventing thrombosis. More |
65141-46-0 | 33 |
Appearance
This product is white or off-white tablets.
Indication
It is suitable for the treatment of coronary heart disease and angina pectoris. It is effective for exertional, spontaneous, post-infarction or mixed angina pectoris. It can be used for patients with angina pectoris accompanied by atrial fibrillation, cardiac enlargement, and patients who need to use other anti-angina drugs with caution.
Usage and Dosage
Oral administration: 1 tablet at a time, 3 times a day; if symptoms do not improve significantly, the dose can be increased to 2 tablets at a time, 3 times a day.
Adverse Reactions
1. Common reactions include headache, dizziness, tinnitus, insomnia, etc. Taking aspirin can alleviate the symptoms, otherwise the drug should be discontinued; if allergic reactions such as rashes occur, the drug should be discontinued. 2. Gastrointestinal symptoms: abdominal pain, diarrhea, loss of appetite, indigestion, nausea, vomiting, constipation, etc., occasionally angular cheilitis, and elevated aminotransferase. 3. Cardiovascular system: palpitations, fatigue, facial flushing, lower limb edema, and can also cause reflex heart rate acceleration, severe hypotension and other reactions.
Precautions
1. It is contraindicated for patients with glaucoma. 2. It is contraindicated for patients with severe liver or kidney diseases.
Special Population Medication
Precautions for children: Not clear yet. Precautions for pregnancy and lactation: Use with caution for pregnant women. Precautions for the elderly: Because the physiological functions of elderly patients are generally weaker and side effects are more likely to occur, it should be used with caution and can be started with a small dose.
Drug Interactions
Not yet clear.
Storage
Sealed and stored away from light.
Packaging Specification
5mg
Validity Period
24 months
Manufacturer
Jiangsu Pingguang Pharmaceutical (Jiaozuo) Co., Ltd.
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Founded in:
2002-03-19 -
Address:
300 meters north of the extension section of Jiefang Avenue, east of Huazhang Road, Fengxian Economic Development Zone -
Tax NO.:
91320321730727420F -
Registered Funds:
14.4522 million yuan -
Email: