Defibrase for injection

Proteolytic enzyme. It can dissolve blood clots, inhibit thrombosis, and improve microcirculation.

Defibrase

This product is white or off-white freeze-dried block or powder, hygroscopic and easily soluble in water.

(1) Acute cerebral infarction, including cerebral thrombosis, cerebral embolism, transient ischemic attack (TIA), and prevention of recurrent cerebral infarction. (2) Myocardial infarction, unstable angina pectoris, and prevention of recurrent myocardial infarction. (3) Vascular diseases of the limbs, including femoral artery embolism, thromboangiitis obliterans, and Raynaud's disease. (4) Blood in a hyperviscosity state, hypercoagulable state, and prethrombotic state. (5) Sudden deafness. (6) Pulmonary embolism.

Before use, dissolve it in an appropriate amount of water for injection or saline, add it to 100ml-250ml of sterile saline, and drip it intravenously for more than 1 hour. Acute attack period: 10 units at a time, once a day, for 3 to 4 consecutive days. Non-acute attack period: 10 units for the first time, 5 to 10 units for maintenance, once a day or every other day, and a course of treatment of two weeks.

Some patients may experience a small amount of bruising, nosebleeds or gum bleeding, or a transient slight increase in GOT or GPT after taking the medicine, which will disappear on their own after stopping the medicine.

Patients with endogenous bleeding tendency and allergic constitution should use with caution. Patients with severe liver and kidney dysfunction should not use this product. (1) The following patients should not use this product: ① Patients with a history of bleeding diseases. ② Patients who have just undergone surgery. ③ Patients with bleeding tendency. ④ Patients who are using drugs with anticoagulant effects and platelet inhibition (such as aspirin). ⑤ Patients who are using antifibrinolytic preparations. ⑥ Patients with severe liver or kidney dysfunction and other conditions such as papillary muscle rupture, ventricular septum perforation, cardiogenic shock, and multiple organ failure. ⑦ Patients with a history of allergy to this product. (2) The following patients should use this product with caution: ① Patients with a history of drug allergy. ② Patients with a history of gastrointestinal ulcers. ③ Patients with sequelae of cerebral thrombosis. ④ Elderly patients over 70 years old.

Precautions for the elderly: Use with caution in patients over 70 years old.

When using this product, avoid using it with salicylic acid drugs (such as aspirin). Anticoagulants can enhance the effect of this product and cause unexpected bleeding; antifibrinolytic drugs can offset the effect of this product and are prohibited from being used in combination.

Keep in a dark place, sealed and stored below 10℃.

5 units

Beijing Science Sun Pharmaceutical Co., Ltd.

• Founded in:

  1999-05-20

• Address:

  No. 8 Xingsheng Street, Beijing Economic and Technological Development Zone, Beijing

• Tax NO.:

  911100007002230889

• Registered Funds:

  481.6664 million yuan

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