Phenolamine granules

The aminopyrine in this product can inhibit the synthesis and release of prostaglandins in the hypothalamus, restore the normal responsiveness of the sensory neurons in the thermoregulatory center and play an antipyretic role; at the same time, it also has an analgesic effect by inhibiting the synthesis of prostaglandins, etc. Aminopyrine can also inhibit the synthesis and release of prostaglandins in local tissues of inflammation, stabilize lysosomal enzymes, affect the phagocytic function of phagocytes and play an anti-inflammatory role. Acetaminophen is a peripheral analgesic. The mechanism of action is to inhibit the synthesis and release of prostaglandins (PGE1) in the thermoregulatory center of the hypothalamus, thereby causing peripheral vasodilation and sweating to achieve an antipyretic effect. At the same time, it can inhibit the effects of PGE1, bradykinin and histamine, increase the pain threshold and produce analgesic effects. Caffeine is a central nervous system stimulant that can excite the cerebral cortex, increase sensitivity to the outside world, and constrict cerebral blood vessels, enhancing the effect of the first two drugs in relieving headaches. Chlorpheniramine maleate has a strong histamine H1 receptor blocking effect, which can alleviate other respiratory symptoms caused by allergies and also has a mild inhibitory effect on the central nervous system.

This product is a compound preparation, its components are: aminopyrine 0.1g, acetaminophen 0.150g, caffeine 30mg, chlorpheniramine maleate 2mg.

This product is colored granules with sweet taste.

Antipyretic and analgesic. Used for colds, fever, headaches, neuralgia, rheumatism, etc.

Take with water. 1 bag at a time, 3 times a day or as directed by your doctor.

The aminopyrine contained in this compound has obvious adverse reactions. Taking aminopyrine may cause vomiting, rash, fever, heavy sweating and stomatitis, etc. In a few cases, it may cause neutropenia, aplastic anemia, exudative erythema, exfoliative dermatitis, glans erosion, etc.

1. It is contraindicated for patients who are allergic to aminopyrine, caffeine or chlorpheniramine maleate. 2. It is contraindicated for patients with gastric ulcer. 3. It is contraindicated for newborns or premature infants.

Precautions for children: It is forbidden to use in newborns or premature infants. Precautions for pregnancy and lactation: A small amount of chlorpheniramine maleate can be excreted through breast milk, and due to the anti-M cholinergic receptor effect of this product, lactation may be inhibited. It is not suitable for lactating women to take it casually. Acetaminophen can pass through the placenta, and pregnant women may have adverse effects on the fetus after taking it. Precautions for the elderly: They are more sensitive to chlorpheniramine maleate, so they should pay attention to reducing the dosage appropriately.

1. Isoniazid and meprobamate can enhance the efficacy of caffeine, increasing the concentration of caffeine in brain tissue by 55%, while the concentration in liver and kidney decreases. 2. Oral contraceptives may slow down the clearance rate of caffeine. 3. Drinking alcohol or taking central nervous system depressants at the same time can enhance the efficacy of antihistamines. 4. This product can enhance the effects of amantadine, anticholinergics, haloperidol, phenothiazines and sympathomimetics. 5. When quinidine is used together with this product, its atropine-like effect is aggravated. 6. This product can be taken together with tricyclic antidepressants to enhance the efficacy of the latter. Long-term or excessive use can cause damage to the central nervous system, liver and kidney function, blood system, etc., manifested as: 1. Irritability, disturbance, tinnitus, dizziness with blind spots or flashing lights, muscle tremors, increased heartbeat and premature beats. 2. Difficulty or pain in urination, dizziness, dryness in the mouth, nose and throat, headache, loss of appetite, nausea, upper abdominal discomfort or stomach pain, rash. Children are prone to irritability, anxiety, difficulty falling asleep and nervousness.

seal

Compound

24 months

North China Pharmaceutical Company.Ltd

• Founded in:

  1992-12-20

• Address:

  No. 388, Heping East Road, Shijiazhuang City

• Tax NO.:

  91130100104397700P

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  1,715,730,370 yuan

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