Tinidazole Sodium Chloride Injection

1. Used for various anaerobic infections, such as sepsis, osteomyelitis, abdominal infection, pelvic infection, lung and bronchial infection, sinusitis, skin cellulitis, oral infection and postoperative wound infection. 2. Used for preoperative preventive medication in colorectal surgery, gynecological surgery and oral surgery.

tinidazole

This product is a colorless or almost colorless clear liquid.

1. Used for various anaerobic infections, such as sepsis, osteomyelitis, abdominal infection, pelvic infection, lung and bronchial infection, sinusitis, skin cellulitis, oral infection and postoperative wound infection. 2. Used for preoperative preventive medication in colorectal surgery, gynecological surgery and oral surgery.

Intravenous drip. 1. Anaerobic infection: 0.8g once, once a day, intravenous drip slowly, generally 5 to 6 days, or according to the condition. 2. Prevention of postoperative anaerobic infection: total amount 1.6g, drip once or twice, the first time 2 to 4 hours before surgery, the second time during surgery or within 12 to 24 hours after surgery.

Adverse reactions are rare and mild, mainly nausea, vomiting, upper abdominal pain, loss of appetite and metallic taste in the mouth, headache, dizziness, itchy skin, rash, constipation and general discomfort. In addition, there may be angioedema, neutropenia, disulfiram-like reaction and dark urine, and occasionally mild phlebitis at the infusion site. High doses can also cause epileptic seizures and peripheral neuropathy.

It is contraindicated for patients who are allergic to this product or azole drugs and those with active central nervous system diseases and blood diseases.

1. This product can inhibit the metabolism of warfarin and other oral anticoagulants, enhance their effects, and cause the prothrombin time to be prolonged. 2. When used in combination with drugs that induce liver microsomal enzymes such as phenytoin sodium and phenobarbital, it can accelerate the metabolism of this product, reduce the blood drug concentration, and slow down the excretion of phenytoin sodium. 3. When used in combination with drugs that inhibit the activity of liver microsomal enzymes such as cimetidine, it can slow down the metabolism and excretion of this product in the liver, prolong the blood elimination half-life (t1/2?) of this product, and the dosage should be adjusted according to the results of blood drug concentration determination. 4. This product interferes with the metabolism of disulfiram. When the two are used together, patients may experience mental symptoms after drinking. Therefore, patients who have used disulfiram within 2 weeks should not use this product again. 5. This product can interfere with the results of serum aminotransferase and lactate dehydrogenase determinations, and can reduce cholesterol and triglyceride levels.

Keep away from light, tightly closed, in a cool place.

200ml: 0.4g tinidazole and 1.8g sodium chloride