Fenoprofen calcium tablets

This product is also a phenylpropionic acid derivative and a non-steroidal anti-inflammatory drug. It reduces the synthesis of prostaglandins by inhibiting cyclooxygenase, thereby reducing tissue congestion and swelling and reducing the sensitivity of peripheral nerve pain. It has an antipyretic effect through the hypothalamic temperature regulation center. It takes effect within 1 hour after oral administration and lasts for 3-4 hours. Toxicology

The chemical name of this product is: alpha-methyl-3-phenoxy-phenylacetic acid calcium dihydrate.

This product is white tablets.

It is suitable for various types of arthritis, including rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gouty arthritis and other soft tissue pain. It is also used for other pains such as dysmenorrhea, toothache, injury and traumatic pain.

Common dosage for adults: Oral. 1. Anti-rheumatic: 0.3-0.6g each time, 3-4 times a day depending on the severity of the condition. 2. Analgesia (mild to moderate pain or dysmenorrhea): 0.2g each time, once every 4-6 hours. The maximum daily limit for adults is 3.2g.

1. Gastrointestinal symptoms are the most common, including nausea, vomiting, heartburn, constipation, indigestion, etc. Severe cases may cause gastric ulcers, bleeding and perforation; 2. Other symptoms include headaches, dizziness, drowsiness, and lower limb edema. Occasionally, leukocytes and platelets may be reduced, and liver enzymes may increase transiently; 3. Allergic rashes and skin itching may also occur.

1. Patients who are allergic to the drug are prohibited from using this drug. 2. Patients with severe renal dysfunction are prohibited from using this drug. 3. Patients with asthma, rhinitis, urticaria, etc. induced by aspirin and other non-steroidal anti-inflammatory analgesics are prohibited from using this drug.

(1) When used with alcohol or other non-steroidal anti-inflammatory drugs, gastrointestinal side effects may increase, and there is a risk of ulcers. Long-term use with acetaminophen may increase kidney toxicity. (2) When used with aspirin or other salicylic acid drugs, the bioavailability of this product may be reduced, the efficacy will not be enhanced, and the incidence of gastrointestinal adverse reactions and bleeding tendency will increase. (3) When used with anticoagulants such as heparin and dicoumarol and platelet aggregation inhibitors, there is an increased risk of bleeding. (4) When used with furosemide, the latter's sodium excretion and antihypertensive effects are weakened. (5) When used with verapamil and nifedipine, the blood concentration of this product increases. (6) This product can increase the blood concentration of digoxin. When used at the same time, the dosage of digoxin should be adjusted. (7) This product can enhance the effect of antidiabetic drugs (including oral hypoglycemic drugs). (8) When used with antihypertensive drugs, this product may affect the antihypertensive effect of the latter. (9) Probenecid can reduce the excretion of this product, increase its blood concentration, and thus increase its toxicity. Therefore, it is advisable to reduce the dosage of this product when used simultaneously. ⑽ This product can reduce the excretion of methotrexate, increase its blood concentration, and even reach toxic levels. Therefore, this product should not be used simultaneously with medium or large doses of methotrexate. ⑾ This product does not affect absorption when taken together with antacids containing aluminum and magnesium. When used together with antacids for a long time, the blood concentration may be significantly reduced. When used together with phenobarbital, the excretion half-life of this product is shortened, which may be related to the increase in liver enzyme activity that accelerates the metabolism of this product. At this time, the dosage of this product needs to be adjusted.

Keep tightly closed.

0.3g (calculated as C15H14O3)

36 months