Enalapril Maleate Tablets
Function and Efficacy
This product is an angiotensin converting enzyme inhibitor. After oral administration, it is hydrolyzed into Enalaprilat in the body, which strongly inhibits angiotensin converting enzyme, reduces the content of angiotensin II, causes systemic vasodilation, and causes blood pressure reduction. It has a significant antihypertensive effect on rat models of renal hypertension II, renal hypertension I, and spontaneous hypertension.
Ingredients
The main ingredient of this product is enalapril maleate.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Enalapril maleateIngredients |
This product is an angiotensin converting enzyme inhibitor. After oral administration, it is hydrolyzed into Enalaprilat in the body, which strongly inhibits angiotensin converting enzyme, reduces the content of angiotensin II, causes systemic vasodilation, and causes blood pressure reduction. It has a significant antihypertensive effect on rat models of renal hypertension II, renal hypertension I, and spontaneous hypertension. More |
76095-16-4 | 35 |
Appearance
This product is white tablets.
Indication
Used to treat essential hypertension.
Usage and Dosage
Oral administration. The initial dose is 5-10 mg per day, divided into 1-2 doses. For patients with severe renal impairment (creatinine clearance rate less than 30 ml/min), the dose is 2.5 mg per day. The dose can be gradually increased according to the blood pressure level. The general effective dose is 10-20 mg per day, and the maximum daily dose should not exceed 40 mg. This product can be used in combination with other antihypertensive drugs, especially diuretics, and the antihypertensive effect is significantly enhanced, but it should not be used in combination with potassium-retaining diuretics.
Adverse Reactions
Symptoms may include dizziness, headache, drowsiness, dry mouth, fatigue, upper abdominal discomfort, nausea, palpitations, chest tightness, cough, flushing, rash, and proteinuria. Reduce the dosage if necessary. If leukopenia occurs, stop taking the drug.
Precautions
Patients who are allergic to this product or have bilateral renal artery stenosis should not use this product. Patients with severe renal impairment should use it with caution.
Special Population Medication
Precautions for children: Use with caution in children. Precautions for pregnancy and lactation: Use with caution in pregnant and lactating women. Precautions for the elderly: This experiment has not been conducted and there is no reliable reference literature.
Drug Interactions
Not yet clear.
Storage
Keep away from light and store in a sealed container.
Packaging Specification
5 mg
Validity Period
36 months