Nimesulide Granules
Function and Efficacy
This product is a non-steroidal anti-inflammatory drug with anti-inflammatory, analgesic and antipyretic effects. Its mechanism of action is not yet fully understood, but it may be mainly related to the inhibition of prostaglandin synthesis, mediator release of leukocytes and oxidative reactions of polymorphonuclear leukocytes.
Ingredients
Mainly nimesulide. Chemical name: 4-nitro-2-phenoxymethanesulfonylanilide. Molecular weight: 308.32
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| NimesulideIngredients |
This product is a non-steroidal anti-inflammatory drug with anti-inflammatory, analgesic and antipyretic effects. Its mechanism of action is not yet fully understood, but it may be mainly related to the inhibition of prostaglandin synthesis, mediator release of leukocytes and oxidative reactions of polymorphonuclear leukocytes. More |
51803-78-2 | 14 |
Appearance
This product is in the form of granules.
Indication
1. This product is a non-steroidal anti-inflammatory drug with anti-inflammatory, analgesic and antipyretic effects. It can be used for chronic joint inflammation (such as rheumatoid arthritis and osteoarthritis, etc.); 2. Pain and inflammation after surgery and acute trauma; pain caused by inflammation of the ear, nose and pharynx; dysmenorrhea; fever caused by upper respiratory tract infection and other symptoms.
Usage and Dosage
This product adopts the shortest possible course of treatment based on the actual clinical situation. Oral administration: for adults, 0.05-0.1g at a time, twice a day, after meals. For children, the usual dose is 5mg/kg body weight/day, divided into 2 to 3 doses. For other precautions, see [Children's Use].
Adverse Reactions
1. Mainly: heartburn, nausea, stomach pain. But the symptoms are mild and short-lived, rarely need to interrupt treatment. In rare cases, patients develop allergic rashes after taking the drug. 2. Even if the use of nimesulide does not produce the above side effects, it should be noted that this product, like other non-steroidal anti-inflammatory drugs, may cause dizziness, drowsiness, gastric ulcer or gastrointestinal bleeding and Stevens-Johnson syndrome.
Precautions
1. It is contraindicated for patients who are allergic to this product, acetylsalicylic acid or other non-steroidal drugs; 2. It is contraindicated for patients with active gastrointestinal bleeding or active gastrointestinal ulcer; 3. It is contraindicated for patients with severe liver dysfunction or severe renal dysfunction (creatinine clearance 30 ml/min); 4. It is not recommended to use this drug during pregnancy.
Special Population Medication
Precautions for children: Only for children over 1 year old, the dosage is 5mg/kg body weight/day, divided into 2 to 3 doses, the maximum dose is no more than 100mg, twice a day. For fever, the course of treatment is no more than 3 days. For rheumatism, the course of treatment should be in accordance with the doctor's advice. Precautions for pregnancy and lactation: Not recommended during pregnancy. Precautions for the elderly: The dosage of elderly patients should be strictly in accordance with the doctor's prescription, and the doctor can appropriately reduce the dosage according to the situation.
Drug Interactions
This product may cross-react with aspirin and other non-steroidal anti-inflammatory drugs. Therefore, it is contraindicated for patients who are allergic to these drugs. This product is a highly protein-bound drug, so it may displace other protein-bound drugs. If vision loss occurs after taking other non-steroidal anti-inflammatory drugs, treatment should be stopped and an ophthalmological examination should be performed.
Storage
Sealed, store in a dry place.
Packaging Specification
50mg
Validity Period
24 months
Manufacturer
Sinopharm Group Jingfang (Anhui) Pharmaceutical Co., Ltd.
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Founded in:
2000-03-07 -
Address:
No. 16 Xuanshui Road, Xuancheng City, Anhui Province -
Tax NO.:
91341800153303918G -
Registered Funds:
39 million yuan -
Email: