Aprotinin for injection

This product is a broad-spectrum protease inhibitor and has an effect on plasmin and the like.

Peptidase inhibitors

Used for open heart surgery with extracorporeal circulation or other surgeries. Inhibits fibrinolytic protein, reduces intraoperative and postoperative bleeding and postoperative intestinal adhesion.

1. Allergic reaction test: Before use, dissolve 1 bottle of this product in 10ml of 5% glucose injection, draw out 1ml, dilute it to 5ml with 5% glucose injection, slowly inject 1ml intravenously, and observe closely for 15 minutes. If an allergic reaction occurs, it cannot be used. 2. Before extracorporeal circulation, add 1680-2800 units of this product (840-1120 units for children) to the pre-filling solution at one time. 3. Bleeding caused by other fibrinolysis: 44.8-67.2 units per day, 11.2-22.4 units per day after the condition is alleviated. 4. Prevention of bleeding: Starting from the day before surgery, inject 11.2 units per day. 5. Prevent postoperative intestinal adhesion: Before the surgical incision is closed, directly inject 11.2-28 units into the abdominal cavity, and do not contact the wound.

Occasionally, nausea, vomiting, diarrhea, etc. may occur. A very small number of patients may experience a transient increase in serum creatinine and allergic and anaphylactic reactions.

It is contraindicated in patients who are allergic to aprotinin.

1 This product can inhibit the antihypertensive effect of angiotensin converting enzyme inhibitors (such as captopril) (it has been reported, but there is no conclusive opinion yet). 2 This product has the effect of antagonizing plasmin (such as alteplase, anistreplase, streptokinase, urokinase, etc.) and can be used to inhibit bleeding caused by these drugs. 3 This product can interfere with the following tests: blood clotting time, serum creatinine kinase (CK), serum creatinine, aminotransferase, etc.

Keep in a dark, airtight container in a cool place.

28 units

Livzon (GROUP) Pharmaceutical FACTORY

• Founded in:

  1989-11-26

• Address:

  No. 38 Chuangye North Road, Jinwan District, Zhuhai City

• Tax NO.:

  91440400617489061P

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