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Levofloxacin Lactate Injection

Function and Efficacy

This product is the levorotatory form of ofloxacin, and its antibacterial activity is about 2 times that of ofloxacin. Its main mechanism of action is to inhibit bacterial DNA gyrase activity and inhibit bacterial DNA replication. It has the characteristics of broad antibacterial spectrum and strong antibacterial effect. It has strong antibacterial activity against most Enterobacteriaceae, such as Klebsiella pneumoniae, Proteus, Salmonella typhi, Shigella, influenza bacillus, some Escherichia coli, Pseudomonas aeruginosa, gonococci, etc. It also has good antibacterial effect against some Staphylococci, Streptococcus pneumoniae, Chlamydia, etc.

Ingredients

Main ingredients and chemical name of this product: The main ingredient of this product is levofloxacin lactate, and its chemical name is: (S)-(-)-9-fluoro-2-,3-dihydro-3-methyl-10(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de][1,4]-benzoxazine-6-carboxylic acid lactate hemihydrate. [Molecular formula] C18H20FN3O4C3H6O31/2H2O [Molecular weight] 460.41

Name Description Content CAS NO. Manufacturer
LEVOFLOXACIN LACTATEIngredients

This product is the levorotatory form of ofloxacin, and its antibacterial activity is about 2 times that of ofloxacin. Its main mechanism of action is to inhibit bacterial DNA gyrase activity and inhibit bacterial DNA replication. It has the characteristics of broad antibacterial spectrum and strong antibacterial effect. It has strong antibacterial activity against most Enterobacteriaceae, such as Klebsiella pneumoniae, Proteus, Salmonella typhi, Shigella, influenza bacillus, some Escherichia coli, Pseudomonas aeruginosa, and gonococci; it also has good antibacterial effect against some Staphylococci, Streptococcus pneumoniae, Chlamydia, etc.

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294662-18-3 11

Appearance

This product is a light yellow-green clear liquid.

Indication

It is suitable for moderate to severe respiratory system, urinary system, digestive system and skin and soft tissue infections caused by sensitive strains of Gram-negative bacteria and Gram-positive bacteria, sepsis, typhoid and paratyphoid dysentery, and urethritis and cervicitis caused by gonococci and Chlamydia trachomatis.

Usage and Dosage

Intravenous drip: Adults: 0.1-0.2g at a time, twice a day, or as directed by a doctor.

Adverse Reactions

Poor appetite, nausea, vomiting, diarrhea, insomnia, dizziness, headache, rash, elevated serum alanine aminotransferase and local irritation symptoms after injection may occur occasionally, but they are generally tolerated and disappear after the treatment.

Precautions

It is contraindicated for people who are allergic to quinolones and patients with epilepsy. [Use in pregnant and lactating women] It is contraindicated for pregnant and lactating women. [Use in children] It is contraindicated for patients under 18 years old.

Special Population Medication

Precautions for children: In animal experiments (puppies, young adult dogs, and young mice), it was found that this product caused abnormal damage to weight-bearing joints, so it is contraindicated for patients under 18 years old. Precautions for pregnancy and lactation: 1. Because the safety of the drug for pregnant women cannot be ensured, it is contraindicated for pregnant women or women who may become pregnant. 2. Because the drug is excreted through breast milk, it is contraindicated for lactating women. If you must take this drug, you should stop breastfeeding. Precautions for the elderly: This product is mainly excreted through the kidneys (see "Pharmacokinetics"), because most elderly patients have low renal function, they may have persistently high blood drug concentrations. Therefore, you should pay attention to the dosage and administer the drug with caution.

Drug Interactions

Not yet clear.

Storage

Keep away from light and store in a sealed container.

Packaging Specification

100ml:0.2g (based on levofloxacin)

Validity Period

24 months

Manufacturer

Heilongjiang Jiangshi Pharmaceutical Co., Ltd.

  • Founded in:

    1998-07-27
  • Address:

    No. 2 Weihai Road, Pingfang Economic and Technological Development Zone, Harbin City, Heilongjiang Province
  • Tax NO.:

    91230199702846035D
  • Registered Funds:

    5 million yuan
  • Website:

  • Email:

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