Chloroquine
Function and Efficacy
Animal experiments have shown that chloroquine has an inhibitory effect on the DNA synthesis of tumor cells, can damage the DNA template of cancer cells, increase the size of cancer cell lysosomes, and lead to rupture. It releases a variety of hydrolases, causing cancer cells to autolyze and die, and can activate intrahepatic microsome enzymes. In the in vitro anti-tumor test of human osteosarcoma cells, the IG after 24 hours of action was (9.3±0.8) mg·I. The IG after 48 hours of action was (2.44±0.28) mg·I, and the IG after 72 hours of action was (1.74±0.18) mg·L~, both 50%, which was significantly different from the control group (P
Ingredients
The chemical name is: 7-chloro-4-oxo-quinoline, and the molecular formula is C9H6CIN0.
Indication
Used for the treatment of breast cancer, lung cancer, liver cancer, leukemia, rectal cancer, colon cancer, bladder cancer, gastric cancer, kidney cancer, pancreatic cancer, osteosarcoma, malignant lymphoma, brain tumors, etc.
Usage and Dosage
Oral administration: 2 capsules at a time, 3 times a day; or 20-30 mg per kg of body weight per day, divided into 3 doses. 4 weeks of continuous administration is a course of treatment.
Adverse Reactions
Gastrointestinal reactions include stomach discomfort, poor appetite, nausea, vomiting, etc. Blood system reactions include decreased white blood cells and decreased hemoglobin.
Precautions
It is contraindicated for those who are allergic to the ingredients of this product.
Drug Interactions
This product has a central nervous system inhibitory effect. When used in combination with central nervous system inhibitors, the latter's dose should be reduced. This product has a liver enzyme induction effect. Pay attention to the resulting drug interactions.
Storage
Store at room temperature, away from light.
Manufacturer
Tonghua Mao Xiang Pharmaceutical Co., Ltd.
-
Founded in:
1992-12-22 -
Address:
No. 567, Xinsheng North Road, Tonghua City, Jilin Province -
Tax NO.:
912205016052208157 -
Registered Funds:
50 million yuan -
Website:
-
Email: