Chorionic Gonadotropin for Injection

This product is a gonadotropin drug. For women, it can promote and maintain the function of the corpus luteum and make the corpus luteum synthesize progesterone. It can promote the formation and maturation of follicles and stimulate ovulation by simulating the peak of physiological luteinizing hormone. For men, it can make the testicles of those with pituitary insufficiency produce androgens, promote testicular descent and the development of male sexual characteristics.

The main ingredient is chorionic gonadotropin, which is added with appropriate excipients and is a freeze-dried sterile product.

This product is white freeze-dried block or powder.

1. Diagnosis and treatment of cryptorchidism before puberty. 2. Male infertility caused by hypopituitarism can be used in combination with urinary gonadotropins. Those with long-term hypogonadotropin function should also be treated with testosterone. 3. Female anovulatory infertility caused by pituitary gonadotropin deficiency is often treated with clomiphene in combination with postmenopausal gonadotropins to promote ovulation. 4. For in vitro fertilization to obtain multiple oocytes, it needs to be used in combination with postmenopausal gonadotropins. 5. Treatment of female luteal insufficiency. 6. Functional uterine bleeding, threatened abortion in early pregnancy, and habitual abortion.

Before use, dissolve it with sterile injection water. Adult dosage 1. For hypogonadism caused by insufficient male gonadotropin function, 1000-4000 units are injected intramuscularly, 2-3 times a week, for several weeks to several months. In order to promote spermatogenesis, the treatment needs to last for 6 months or longer. If the sperm count is less than 5 million/ml, urinary gonadotropin should be used in combination for about 12 months. 2. Ovulation induction, for female anovulatory infertility or in vitro fertilization, 5000-10000 units are injected intramuscularly one day after the last administration of postmenopausal gonadotropin or 5-7 days after the last administration of clomiphene, and the treatment is continued for 3-6 cycles. If there is no effect, stop the drug. 3. For luteal insufficiency, 1500 units are injected intramuscularly every other day from the date of ovulation on the 15th to 17th day of the menstrual period, and it is used for 5 times in a row. It can be adjusted according to the patient's response. After pregnancy, the original dose must be maintained until 7-10 weeks of pregnancy. 4. Functional uterine bleeding, 1000-3000 units intramuscular injection. Habitual abortion, threatened abortion, 1000-5000 units intramuscular injection. Pediatric dosage 1) Testicular function test for developmental retardation, 2000 units intramuscular injection, once a day, for 3 consecutive days. 2) Prepubertal cryptorchidism, 1000-5000 units intramuscular injection, 2-3 times a week, discontinue use after good effects appear. The total number of injections should not exceed 10 times.

1 When used to promote ovulation, the most common symptoms are ovarian cysts or mild to moderate ovarian enlargement, accompanied by mild bloating, stomach pain, and pelvic pain, which can generally subside within 2 to 3 weeks. Rarely, severe ovarian hyperstimulation syndrome occurs. Due to the significant increase in vascular permeability, body fluids rapidly accumulate in the chest, abdominal and pericardial cavities, causing a variety of complications, such as decreased blood volume, electrolyte imbalance, hemoconcentration, abdominal hemorrhage, thrombosis, etc. Clinical manifestations include severe pain in the abdomen or pelvic region, indigestion, edema, decreased urine volume, nausea, vomiting or diarrhea, shortness of breath, swelling of the lower limbs, etc. It often occurs 7 to 10 days after ovulation or after the end of treatment. Severe reactions can be life-threatening. 2 When used to treat cryptorchidism, male precocious puberty may occasionally occur, manifested as acne, enlarged penis and testicles, increased pubic hair growth, and rapid height growth. 3 Less common adverse reactions include: breast enlargement, headache, irritability, depression, and fatigue. 4 Occasionally, there is local pain and allergic rash at the injection site. 5. Using this product to induce ovulation may increase the rate of multiple births or cause neonatal immaturity, premature birth, etc.

Patients suspected of pituitary hyperplasia or tumors, prostate cancer or other androgen-related tumors are contraindicated (it may promote sexual development). Patients with precocious puberty, undiagnosed vaginal bleeding, uterine fibroids, ovarian cysts or ovarian enlargement, thrombophlebitis, and a history of allergy to gonad-stimulating hormones are also contraindicated.

When used in combination with pituitary gonadotropin (such as HMG), adverse reactions may increase and should be used with caution.

Keep tightly closed in a cool, dark place.

2000 units

24 months.

Livzon (GROUP) Pharmaceutical FACTORY

• Founded in:

  1989-11-26

• Address:

  No. 38 Chuangye North Road, Jinwan District, Zhuhai City

• Tax NO.:

  91440400617489061P

• Registered Funds:

  450 million yuan

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