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Diethylstilbestrol Tablets

Function and Efficacy

This product is a synthetic non-steroidal estrogen. Its main effects are: ① Promote the normal development of female organs and secondary sexual characteristics. ② Promote endometrial hyperplasia and vaginal epithelial keratinization. ③ Enhance uterine contraction and increase the sensitivity of the uterus to oxytocin. ④ Small doses stimulate and large doses inhibit the secretion of anterior pituitary gonadotropin and prolactin. ⑤ Anti-androgenic effect.

Ingredients

The main ingredient of this product is diethylstilbestrol.

Name Description Content CAS NO. Manufacturer
DiethylstilbestrolIngredients

Artificially synthesized non-steroidal estrogen. Its main effects are: ① Promote the normal development of female organs and secondary sexual characteristics. ② Promote endometrial hyperplasia and vaginal epithelial keratinization. ③ Enhance uterine contraction and increase the sensitivity of the uterus to oxytocin. ④ Small doses stimulate while large doses inhibit the secretion of anterior pituitary gonadotropin and prolactin. ⑤ Anti-androgenic effect.

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Indication

1. Supplement the lack of estrogen in the body, such as atrophic vaginitis, female gonadal dysgenesis, menopausal syndrome, senile vulvar dryness and vaginitis, after oophorectomy, primary ovarian agenesis. 2. Breast cancer, postmenopausal and male advanced breast cancer, those who cannot undergo surgery. 3. Prostate cancer, advanced patients who cannot undergo surgery. 4. Prevent postpartum lactation and milk withdrawal (or relapse).

Usage and Dosage

1 Oral administration, used to supplement the body's deficiency, 0.25~0.5mg per day, stop taking the medicine for one week after 21 days, take it cyclically, generally 3 cycles can be used (start taking the medicine from the 5th day of menstruation); 2 For breast cancer, 15mg per day, stop taking the medicine if there is no improvement within 6 weeks; 3 For prostate cancer, start with 1~3mg per day, increase and then decrease according to the condition; maintenance dose is 1mg per day, for 2-3 months; 4 To prevent postpartum lactation and milk withdrawal, 5mg once, 3 times a day, for 3 consecutive days.

Adverse Reactions

1. May cause irregular vaginal bleeding, uterine hypertrophy, frequent urination or painful urination. 2. May sometimes cause thrombosis and abnormal heart function. 3. May sometimes cause abnormal liver function, hyperlipidemia, sodium retention. 4. May cause digestive tract nausea, vomiting, anorexia symptoms and mental symptoms such as headache and dizziness.

Precautions

1 Pregnant women are prohibited from using this product (it may increase the incidence of vaginal adenosis and adenocarcinoma in the second generation of women, and increase the incidence of male reproductive tract abnormalities and sperm abnormalities). 2 Patients with a history of thrombophlebitis and pulmonary embolism are prohibited from using this product. 3 Patients with estrogen-related tumors, unconfirmed irregular vaginal bleeding, and hypertension are prohibited from using this product.

Storage

Keep away from light and store in sealed container.

Packaging Specification

1mg

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