Children's Paracetamol and Phenylephrine Granules
Function and Efficacy
The acetaminophen in this product produces analgesic effects mainly by inhibiting the synthesis of prostaglandins (inhibiting prostaglandin synthase) and blocking the impulses of pain nerve endings. The latter may be related to the inhibition of the synthesis of prostaglandins or other substances that can sensitize pain receptors (such as 5-hydroxytryptamine, bradykinin, etc.). The antipyretic effect is produced by the peripheral vasodilation of the hypothalamic thermoregulatory center, and works by increasing blood flow, sweating and heat loss in the skin. Chlorpheniramine maleate is an antihistamine that competitively blocks histamine (H1) receptors, relieves allergic symptoms, and can relieve symptoms such as nasal congestion, runny nose, and sneezing caused by colds. Artificial bezoar has antipyretic and tranquilizing effects.
Ingredients
This product is a compound preparation, each bag contains 0.125g of acetaminophen, 0.5mg of chlorpheniramine maleate, and 5mg of artificial bezoar. The auxiliary material is sucrose.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Chlorphenamine maleateIngredients |
It is an antihistamine that competitively blocks histamine (H1) receptors, relieves allergic symptoms, and can relieve symptoms such as nasal congestion, runny nose, and sneezing caused by colds. More |
113-92-8 | 28 | |
| Atificial Cow-bezoarIngredients |
It has antipyretic and sedative effects More |
1002-00-2 | 2 |
Appearance
This product is light orange-yellow granules.
Indication
It is suitable for relieving symptoms such as fever, headache, limb pain, sneezing, runny nose, nasal congestion, sore throat, etc. caused by common cold and influenza in children.
Usage and Dosage
Take with warm water. For children, take according to age and weight. (3~4 days)
Adverse Reactions
1 In a few cases, agranulocytosis, methemoglobinemia, allergic dermatitis (rash, skin itching, etc.), liver damage, thrombocytopenia, drowsiness, etc. may occur; 2 Long-term and large-scale use of the drug, especially in those with impaired renal function, may cause renal colic or acute renal failure (oliguria, uremia) or chronic renal failure (analgesic nephropathy).
Precautions
1. Patients who are allergic to any of the ingredients in this product are prohibited from using it; 2. Patients with active peptic ulcers are prohibited from using it; 3. Neonates or premature infants are not suitable for using this product; 4. Pregnant and lactating women are prohibited from using it. The acetaminophen and artificial bezoar in this product can pass through the placenta, which may have adverse effects on the fetus, and are toxic to the embryo and can cause teratogenesis; except for the artificial bezoar, which is unknown, all other ingredients can be secreted through breast milk, so pregnant and lactating women are prohibited from using it.
Special Population Medication
Precautions for children: Forbidden to use in newborns or premature infants. Precautions for pregnancy and lactation: The acetaminophen and artificial bezoar in this product can pass through the placenta, which may cause adverse effects on the fetus, and are toxic to the embryo and can cause teratogenesis; except for the artificial bezoar, which is unknown, all other ingredients can be secreted through breast milk, so it is forbidden for pregnant and lactating women. Precautions for the elderly: Not yet clear.
Drug Interactions
1. Long-term use of this product by patients who use barbiturates (such as phenobarbital) or antispasmodics (such as belladonna) may cause liver damage; 2. When this product is used together with chloramphenicol, it may enhance the toxicity of the latter; 3. Large-scale or long-term use of this product may reduce the synthesis of coagulation factors in the liver, thus enhancing the anticoagulant effect of anticoagulants; 4. Long-term and large-scale use of this product together with aspirin, other salicylate preparations or other non-steroidal anti-inflammatory drugs may significantly increase the risk of nephrotoxicity.
Storage
seal.
Validity Period
24 months.
Manufacturer
Guangxi Shengte Pharmaceutical Co., Ltd.
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Founded in:
2002-02-07 -
Address:
No. 10, Hexi Avenue Extension, Dapu Town, Liucheng County, Liuzhou City, Guangxi Zhuang Autonomous Region -
Tax NO.:
914502227351649038 -
Registered Funds:
38.748216 million yuan -
Website:
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Email: