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Fenofibrate Capsules (II)

Function and Efficacy

Fenofibrate Capsules II is a blood lipid regulating drug of clofibric acid derivatives. It reduces blood low-density lipoprotein, cholesterol and triglycerides by inhibiting the production of very low-density lipoprotein and triglycerides and increasing their catabolism at the same time. It also increases the production of apolipoprotein A1 and A11, thereby increasing high-density lipoprotein. This product also has the effect of reducing blood uric acid in normal people and patients with hyperuricemia. Animal experiments have shown that fenofibrate is teratogenic and carcinogenic.

Ingredients

The main ingredient of this product is: fenofibrate.

Name Description Content CAS NO. Manufacturer
FenofibrateIngredients

By inhibiting the production of very low-density lipoprotein and triglyceride and increasing their catabolism, it reduces blood low-density lipoprotein, cholesterol and triglyceride; it also increases the production of apolipoprotein A1 and A11, thereby increasing high-density lipoprotein. It also has the effect of reducing blood uric acid in normal people and patients with hyperuricemia. Animal experiments have shown that fenofibrate is teratogenic and carcinogenic.

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49562-28-9 63

Appearance

The content of this product is white or off-white granules or powder.

Indication

Hypercholesterolemia (type IIa).

Usage and Dosage

This drug can be taken for a long time with dietary control, and the efficacy should be monitored regularly. Oral administration. 0.2g once a day, taken with meals. When cholesterol levels are normal, it is recommended to reduce the dose.

Adverse Reactions

When used in combination with other fibrates, muscle dysfunction (diffuse pain, tenderness, muscle weakness) and rare severe rhabdomyolysis have been reported. Most of these adverse reactions are reversible after discontinuation of the drug. Occasionally, dyspepsia, elevated transaminases, and allergic skin reactions have been reported.

Precautions

Not yet clear.

Special Population Medication

Precautions for children: Children are prohibited. Precautions for pregnancy and lactation: Pregnant and lactating women are prohibited. There is no experimental data for this product for humans. Precautions for the elderly: It is recommended to use the normal adult dose. If there is renal impairment, the dose can be reduced.

Drug Interactions

This product should be used with caution with HMG-CoA reductase inhibitors, such as pravastatin, fluvastatin, simvastatin, etc., which may cause myalgia, rhabdomyolysis, increased blood creatine phosphokinase and other myopathy, and the drug should be discontinued in severe cases. This product should be used in combination with bile acid binding resins, such as cholestyramine, etc., and fenofibrate should be taken at least 1 hour before or 4 to 6 hours after taking these drugs. Because bile acid binding drugs can also combine with other drugs taken at the same time, thereby affecting the absorption of other drugs.

Storage

Keep away from light and store in sealed container.

Packaging Specification

0.2g

Validity Period

24 months

Manufacturer

Anhui Pioneer Pharmaceutical Co., Ltd.

  • Founded in:

    2004-01-14
  • Address:

    No. 35, Hongfeng Road, Hefei High-tech Industrial Development Zone
  • Tax NO.:

    91340100758501263P
  • Registered Funds:

    20 million yuan
  • Website:

  • Email:

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