Aminoflavone Tablets
Function and Efficacy
It is a compound antipyretic and analgesic drug. Aminopyrine and phenacetin both have antipyretic and analgesic effects, can inhibit the synthesis and release of prostaglandins in the hypothalamus, restore the normal responsiveness of the receptor neurons in the temperature regulation center and play an antipyretic role; at the same time, it also plays an analgesic role by inhibiting the synthesis of prostaglandins. Aminopyrine can also inhibit the synthesis and release of prostaglandins in local inflammatory tissues, stabilize lysosomal enzymes, and affect the phagocytic function of phagocytes to play an anti-inflammatory role. Caffeine is a central nervous system stimulant that can excite the cerebral cortex, increase sensitivity to the outside world, and constrict cerebral blood vessels, which enhances the effect of the first two drugs in relieving headaches.
Ingredients
This product is a compound preparation, and its components are: each tablet contains 100 mg of aminopyrine, 150 mg of phenacetin and 45 mg of caffeine.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| PhenacetinIngredients |
It has antipyretic and analgesic effects, can inhibit the synthesis and release of prostaglandins in the hypothalamus, restore the normal responsiveness of the receptor neurons in the body temperature regulation center and have an antipyretic effect; it exerts analgesic effect by inhibiting the synthesis of prostaglandins, etc. More |
62-44-2 | 7 |
Appearance
This product is white.
Indication
For fever and mild to moderate pain
Usage and Dosage
Take 1-2 tablets at a time when needed, 1-3 times a day.
Adverse Reactions
Both aminopyrine and phenacetin contained in this compound have obvious adverse reactions. Taking aminopyrine may cause vomiting, rash, fever, heavy sweating and stomatitis, etc. A few cases may cause neutropenia, aplastic anemia, exudative erythema, exfoliative dermatitis, glans erosion, etc. Long-term use of phenacetin can cause renal papillary necrosis, interstitial nephritis and acute renal failure, and may even induce renal pelvic cancer and bladder cancer, and may also cause drug dependence. Phenacetin also easily causes hemoglobin to form methemoglobin, which reduces the oxygen-carrying capacity of the blood and leads to cyanosis. It can also cause hemolysis, liver damage, and has a certain toxicity to the retina.
Precautions
It is contraindicated for patients with severe liver and kidney dysfunction, hemolytic anemia, and allergies to aminopyrine, phenacetin, or caffeine. It is not suitable for preschool children.
Special Population Medication
Precautions for children: Not suitable for preschool children. Precautions for pregnancy and lactation: Not recommended. Precautions for the elderly: Elderly patients are prone to toxic reactions due to decreased liver and kidney function. They should be used with caution or in a reduced dosage.
Drug Interactions
See drug interactions for each ingredient.
Storage
Keep away from light and store in airtight container.
Packaging Specification
1.095g
Validity Period
24 months