Fengshiding Capsule

This product is a calcium influx blocker (also known as a calcium channel blocker or calcium ion antagonist), which blocks extracellular calcium ions from entering myocardial and vascular smooth muscle cells through the calcium ion channels (slow channels) of the cell membrane. This product directly relaxes vascular smooth muscle, dilates peripheral arterioles, reduces peripheral resistance (afterload), and dilates coronary arteries, which can relieve coronary artery spasm, and has the effects of anti-hypertension and relieving angina pectoris.

The chemical name of this product is: -ethyl-methyl-(-aminoethoxymethyl)-(-chlorophenyl)-,-dihydro-,-methyl-,-pyridinedicarboxylate benzenesulfonate. Molecular formula: CHClNO·CHOS, molecular weight:.

This product is white tablets.

The usual starting oral dose is 5 mg, once a day, and the maximum dose is no more than 10 mg, once a day. Thin people, those with weak constitutions, elderly patients, or those with impaired liver function should start taking the drug from 2.5 mg, once a day; those who take other antihypertensive drugs in combination should also start taking the drug from this dose. The dosage is adjusted according to individual needs, and the adjustment period should be no less than 7-14 days so that the doctor can fully evaluate the patient's response to the dose. However, the adjustment speed can be accelerated under the premise of clinical guarantee. The recommended dose for the treatment of angina pectoris is 5-10 mg, and the elderly patients or those with impaired liver function need to reduce the dose.

Patients tolerate this product well. The most common side effects are headache, edema, fatigue, insomnia, nausea, abdominal pain, flushing, palpitations and dizziness. Less common side effects are itching, rash, dyspnea, weakness, muscle cramps and indigestion. Similar to other calcium antagonists, there are very few reports of adverse reactions such as myocardial infarction and chest pain, and these adverse reactions cannot be clearly distinguished from the patient's underlying diseases. No abnormal laboratory test parameters related to this product have been found.

It is contraindicated in patients who are allergic to dihydropyridine calcium antagonists.

Precautions for children: Children should not take this product. Precautions for pregnancy and lactation: Pregnant women should not take this product.

This product is safe to be used in combination with the following drugs: thiazide diuretics, beta-blockers, angiotensin converting enzyme inhibitors, long-acting nitrates, sublingual nitroglycerin, nonsteroidal anti-inflammatory drugs, antibiotics and oral hypoglycemic drugs. In healthy volunteers, the combination of this product with digoxin did not change the blood concentration or renal clearance of digoxin, and the pharmacokinetics of this product did not change when combined with cimetidine. In vitro research data show that this product has no effect on the plasma protein binding rate of digoxin, phenytoin, warfarin or indomethacin. In healthy male volunteers, the use of this product with warfarin did not affect the changes in warfarin on prothrombin time.

Keep in a light-proof and airtight container.

Each tablet contains 0.3g

30 months.