Cefoxitin Sodium for Injection

Cefuroxime Sodium for Injection kills bacteria by inhibiting bacterial cell wall synthesis, and due to the structural characteristics of this product, it has a high resistance to beta-lactamase produced by bacteria. The following common clinical Gram-positive, Gram-negative aerobic and anaerobic pathogens are highly sensitive to this product.

(6R,7S)-3-Hydroxymethyl-7-methoxy-8-oxo-7-(2-(2-thiophene, acetylamino))-5-thio-azabicyclo-[4,2,0]-oct-2-ene-acetic anhydride ester sodium salt

White to off-white powder with a slight peculiar odor.

It is suitable for the following infections caused by bacteria that are sensitive to this product: upper and lower respiratory tract infections; urinary tract infections including complications of gonorrhea; peritonitis and other intra-abdominal and pelvic infections; sepsis (including typhoid fever); gynecological infections; bone and joint soft tissue infections; endocarditis, etc.

Intramuscular injection, intravenous injection or intravenous drip. The usual dosage for adults is 1-2g (1-2 bottles)/time, once every 6-8 hours. Or adjust the dosage according to the sensitivity of the pathogen and the condition.

1. Occasionally, gastrointestinal reactions such as nausea, vomiting, decreased appetite, abdominal pain, diarrhea, and constipation may occur. 2. Occasionally, allergic reactions such as rash, urticaria, erythema, and drug fever may occur; rare symptoms of anaphylactic shock may occur. 3. A small number of patients may experience abnormal liver and kidney function after taking the drug. 4. Long-term and high-dose use of this product may cause dysbacteriosis and secondary infection. It may also cause vitamin K and vitamin B deficiency. 5. Intramuscular injection sites may cause nodules and pain; excessive or too fast intravenous injections may cause burning sensations and vascular pain, and severe cases may cause thrombophlebitis.

It is contraindicated in patients who are allergic to cefoxitin and other cephalosporins.

1. When cefoxitin sodium is used in combination with aminoglycoside antibiotics, it has a synergistic antibacterial effect, but the combination will increase nephrotoxicity. 2. When cefoxitin sodium is used in combination with strong diuretics such as furosemide, it can increase nephrotoxicity. 3. When cefoxitin sodium is used in combination with probenecid, it can delay the excretion of this product, increase the blood concentration of cefoxitin and prolong its half-life. 4. Cefoxitin sodium can affect alcohol metabolism, increase the concentration of acetaldehyde in the blood, and lead to disulfiram-like reactions (facial flushing, headache, dizziness, abdominal pain, stomach pain, nausea, vomiting, shortness of breath, increased heart rate, decreased blood pressure, as well as drowsiness, hallucinations, etc.).

Keep tightly closed in a cool, dark place.

1.0g (calculated as C16H17N3O7S2)

24 months.

Guangdong Bozhou Pharmaceutical Co., Ltd.

• Founded in:

  2000-12-07

• Address:

  Green Industrial Park, Jiedong Economic Development Zone, Jieyang City

• Tax NO.:

  9144520372599310X7

• Registered Funds:

  20 million yuan

• Email:

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